8ZQW
The crystal structure of PDE4D with isoaurostatin derivatives 2-9
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | 3',5'-cyclic-AMP phosphodiesterase 4D | polymer | 506 | 57758.4 | 2 | UniProt (Q08499) Pfam (PF18100) Pfam (PF00233) | Homo sapiens (human) | DPDE3,PDE43,cAMP-specific phosphodiesterase 4D |
| 2 | C, F (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D, G (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | E, H (A, B) | (3~{Z})-3-[[4-[bis(fluoranyl)methoxy]-3-cyclopentyloxy-phenyl]methylidene]-6-oxidanyl-1~{H}-indol-2-one | non-polymer | 387.4 | 2 | Chemie (A1D8Q) | |||
| 5 | I, J (A, B) | water | water | 18.0 | 171 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 115516.8 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 954.2 | |
| All* | Total formula weight | 116471.0 |
