8ZQ8
SARS-Cov-2 3CL protease in complex with macrocyclic inhibitor CG-1039
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 3C-like proteinase nsp5 | polymer | 316 | 34735.6 | 1 | UniProt (P0DTD1) Pfam (PF05409) | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2) | 3CL-PRO,3CLp,Main protease,Mpro,Non-structural protein 5,nsp5,SARS coronavirus main proteinase |
| 2 | B (A) | CG-1039 | non-polymer | 580.7 | 1 | Chemie (A1D8T) | |||
| 3 | C (A) | water | water | 18.0 | 396 | Chemie (HOH) |
Sequence modifications
A: 1 - 306 (UniProt: P0DTD1)
| PDB | External Database | Details |
|---|---|---|
| Gly -9 | - | linker |
| Pro -8 | - | linker |
| Leu -7 | - | linker |
| Gly -6 | - | linker |
| Ser -5 | - | linker |
| Ser -4 | - | linker |
| Ala -3 | - | linker |
| Val -2 | - | linker |
| Leu -1 | - | linker |
| Gln 0 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34735.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 580.7 | |
| All* | Total formula weight | 35316.2 |
