8ZML

Structure of TNIK with inhibitor

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	TRAF2 and NCK-interacting protein kinase	polymer	303	34862.9	2	UniProt (Q9UKE5) Pfam (PF00069)	Homo sapiens (human)
2	C, G (A, B)	Rentosertib	non-polymer		487.6	2	Chemie (A1D8H)
3	D, E (A)	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)
4	F, H (A, B)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
5	I, J (A, B)	water	water		18.0	144	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	69725.9
Non-Polymers*	Number of molecules	6
	Total formula weight	1147.9
All*	Total formula weight	70873.8

*Water molecules are not included.