8ZMC

Dengue 3 NS5 methyltransferase bound to S-Adenosyl-L-homocysteine and Herbacetin

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Dengue 3 NS5 methyltransferase	polymer	284	32049.8	2	UniProt (C1KBQ3) Pfam (PF01728) UniProt (by SIFTS) (V9TQY8)	dengue virus type 3	Genome polyprotein
2	C, I (A, B)	S-ADENOSYL-L-HOMOCYSTEINE	non-polymer		384.4	2	Chemie (SAH)
3	D (A)	Herbacetin	non-polymer		302.2	1	Chemie (A1L1Z)
4	E, F, G, H, J (A, B)	GLYCEROL	non-polymer		92.1	5	Chemie (GOL)

Sequence modifications

A, B: 1 - 265 (UniProt: C1KBQ3)

PDB	External Database	Details
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
Ser -12	-	expression tag
Ser -11	-	expression tag
Gly -10	-	expression tag
Leu -9	-	expression tag
Val -8	-	expression tag
Pro -7	-	expression tag
Arg -6	-	expression tag
Gly -5	-	expression tag
Ser -4	-	expression tag
His -3	-	expression tag
Met -2	-	expression tag
Ala -1	-	expression tag
Ser 0	-	expression tag
Lys 163	Arg 2653	conflict
Ala 188	Thr 2678	conflict

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	64099.5
Non-Polymers*	Number of molecules	8
	Total formula weight	1531.5
All*	Total formula weight	65631.1

*Water molecules are not included.