8ZLY

Crystal structure of Streptococcus pneumoniae pyruvate kinase in complex with oxalate and fructose 1,6-bisphosphate and UDP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Pyruvate kinase	polymer	521	56993.6	8	UniProt (Q8DQ84) Pfam (PF00224) Pfam (PF02887)	Streptococcus pneumoniae R6
2	AA, GA, I, MA, O... (D, E, A, F, B...)	1,6-di-O-phosphono-beta-D-fructofuranose	non-polymer		340.1	8	Chemie (FBP)
3	BA, CA, HA, IA, J... (D, E, A, F, B...)	MAGNESIUM ION	non-polymer		24.3	15	Chemie (MG)
4	DA, JA, L, PA, R... (D, E, A, F, B...)	URIDINE-5'-DIPHOSPHATE	non-polymer		404.2	7	Chemie (UDP)
5	AB, EA, KA, M, QA... (H, D, E, A, F...)	POTASSIUM ION	non-polymer		39.1	8	Chemie (K)
6	BB, FA, LA, N, RA... (H, D, E, A, F...)	OXALATE ION	non-polymer		88.0	8	Chemie (OXL)
7	CB, DB, EB, FB, GB... (A, B, C, D, E...)	water	water		18.0	3849	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H: 1 - 501 (UniProt: Q8DQ84)

PDB	External Database	Details
Met -19	-	initiating methionine
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	455948.7
Non-Polymers*	Number of molecules	46
	Total formula weight	6931.6
All*	Total formula weight	462880.3

*Water molecules are not included.