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8ZKP

Cryo-EM structure of the efflux transporter MmpL5/MmpS5 from Mycobacterium tuberculosis, C3 symmetry

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, D, G
(A, B, E)
Siderophore exporter MmpL5polymer964104874.73UniProt (P9WJV1)
Pfam (PF03176)
Mycobacterium tuberculosis H37Rv
2B, E, H
(F, C, G)
Siderophore export accessory protein MmpS5polymer14215261.53UniProt (P9WJS7)
Pfam (PF05423)
Mycobacterium tuberculosis H37Rv
3C, F, I
(H, D, I)
Meromycolate extension acyl carrier proteinpolymer9910743.93UniProt (A0R0B3)
Pfam (PF00550)
Mycolicibacterium smegmatis MC2 155ACP
4J, K, O, P, T...
(A, B, E)
CARDIOLIPINnon-polymer1464.06Chemie (CDL)
5L, M, Q, R, V...
(A, B, C, E, G)
(1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATEnon-polymer720.06Chemie (PEV)
6N, S, X
(H, D, I)
N~3~-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-N-(2-sulfanylethyl)-beta-alaninamidenon-polymer358.33Chemie (PN7)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains9
Total formula weight392640.0
Non-Polymers*Number of molecules15
Total formula weight14179.4
All*Total formula weight406819.3
*Water molecules are not included.

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PDB entries from 2025-06-18

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