8ZKN

CryoEM structure of Thyroid Hormone Transporter MCT8 bound with silychristin

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Monocarboxylate transporter 8	polymer	539	59559.1	2	UniProt (P36021) Pfam (PF07690)	Homo sapiens (human)	MCT 8,Monocarboxylate transporter 7,MCT 7,Solute carrier family 16 member 2,X-linked PEST-containing transporter
2	C, F (A, B)	(2~{R},3~{R})-2-[(2~{S},3~{R})-3-(hydroxymethyl)-2-(3-methoxy-4-oxidanyl-phenyl)-7-oxidanyl-2,3-dihydro-1-benzofuran-5-yl]-3,5,7-tris(oxidanyl)-2,3-dihydrochromen-4-one	non-polymer		482.4	2	Chemie (A1IET)
3	D (A)	1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE	non-polymer		790.1	1	Chemie (PC1)
4	E, G (A, B)	2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol	non-polymer		516.8	2	Chemie (DU0)
5	H, I (A, B)	water	water		18.0	8	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	119118.1
Non-Polymers*	Number of molecules	5
	Total formula weight	2788.5
All*	Total formula weight	121906.6

*Water molecules are not included.