8ZK3

Cryo-EM structure of pAg-bound BTN2A1-BTN3A1-BTN3A2 in complex with Vgamma9-Vdelta2 TCR (G115 genotype), another TCR focused

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Butyrophilin subfamily 2 member A1	polymer	534	60684.5	2	UniProt (Q7KYR7) Pfam (PF07686) Pfam (PF22705) Pfam (PF13765) Pfam (PF00622)	Homo sapiens (human)
2	C (D)	T cell receptor delta variable 2,T cell receptor delta constant 1	polymer	239	26489.0	1		Homo sapiens
3	D (G)	T cell receptor gamma variable 9,T cell receptor gamma constant 1	polymer	252	28328.3	1		Homo sapiens

Sequence modifications

A, B: 29 - 527 (UniProt: Q7KYR7)

PDB	External Database	Details
Met 7	-	initiating methionine
Asp 8	-	expression tag
Met 9	-	expression tag
Arg 10	-	expression tag
Val 11	-	expression tag
Pro 12	-	expression tag
Ala 13	-	expression tag
Gln 14	-	expression tag
Leu 15	-	expression tag
Leu 16	-	expression tag
Gly 17	-	expression tag
Leu 18	-	expression tag
Leu 19	-	expression tag
Leu 20	-	expression tag
Leu 21	-	expression tag
Trp 22	-	expression tag
Leu 23	-	expression tag
Ser 24	-	expression tag
Gly 25	-	expression tag
Ala 26	-	expression tag
Arg 27	-	expression tag
Cys 28	-	expression tag
Gly 528	-	expression tag
Ser 529	-	expression tag
Ser 530	-	expression tag
Gly 531	-	expression tag
Met 532	-	expression tag
Asp 533	-	expression tag
Tyr 534	-	expression tag
Lys 535	-	expression tag
Asp 536	-	expression tag
Asp 537	-	expression tag
Asp 538	-	expression tag
Asp 539	-	expression tag
Lys 540	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	176186.1
All*	Total formula weight	176186.1

*Water molecules are not included.