8ZJV
Crystal Structure of the ERK2 complexed with 5-Iodotubercidin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Mitogen-activated protein kinase 1 | polymer | 351 | 40758.9 | 1 | UniProt (P28482) Pfam (PF00069) | Homo sapiens (human) | MAP kinase 1,MAPK 1,ERT1,Extracellular signal-regulated kinase 2,ERK-2,MAP kinase isoform p42,p42-MAPK,Mitogen-activated protein kinase 2,MAP kinase 2,MAPK 2 |
| 2 | B (A) | (2R,3R,4S,5R)-2-(4-AMINO-5-IODO-7H-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-(HYDROXYMETHYL)TETRAHYDROFURAN-3,4-DIOL | non-polymer | 392.1 | 1 | Chemie (5ID) PubChem (1830) PubChem (97297) PubChem (6419781) PubChem (9886793) PubChem (14221929) PubChem (16760523) PubChem (23919584) PubChem (25880707) PubChem (26248662) PubChem (35028380) PubChem (46875276) PubChem (45039587) PubChem (51386958) PubChem (51537014) PubChem (59583554) PubChem (59583625) PubChem (134695308) | |||
| 3 | C, D, E (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 4 | F, G, H, I (A) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 5 | J (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) PubChem (312) | |||
| 6 | K (A) | water | water | 18.0 | 304 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 40758.9 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 998.1 | |
| All* | Total formula weight | 41756.9 |
