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8ZJV

Crystal Structure of the ERK2 complexed with 5-Iodotubercidin

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Mitogen-activated protein kinase 1polymer35140758.91UniProt (P28482)
Pfam (PF00069)
Homo sapiens (human)MAP kinase 1,MAPK 1,ERT1,Extracellular signal-regulated kinase 2,ERK-2,MAP kinase isoform p42,p42-MAPK,Mitogen-activated protein kinase 2,MAP kinase 2,MAPK 2
2B
(A)
(2R,3R,4S,5R)-2-(4-AMINO-5-IODO-7H-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-(HYDROXYMETHYL)TETRAHYDROFURAN-3,4-DIOLnon-polymer392.11Chemie (5ID)
3C, D, E
(A)
1,2-ETHANEDIOLnon-polymer62.13Chemie (EDO)
4F, G, H, I
(A)
SULFATE IONnon-polymer96.14Chemie (SO4)
5J
(A)
CHLORIDE IONnon-polymer35.51Chemie (CL)
6K
(A)
waterwater18.0304Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight40758.9
Non-Polymers*Number of molecules9
Total formula weight998.1
All*Total formula weight41756.9
*Water molecules are not included.

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PDB entries from 2025-07-16

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