8ZJL

Structure of DOCK5/ELMO1/Rac1 core (RhoG/DOCK5/ELMO1/Rac1 dataset, class 4)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D (A, D)	Engulfment and cell motility protein 1	polymer	733	84337.7	2	UniProt (Q92556) Pfam (PF11841) Pfam (PF04727) Pfam (PF16457)	Homo sapiens (human)	Protein ced-12 homolog
2	B, E (B, E)	Dedicator of cytokinesis protein 5	polymer	1648	191492.1	2	UniProt (Q9H7D0) Pfam (PF00018) Pfam (PF16172) Pfam (PF14429) Pfam (PF06920) Pfam (PF20422) Pfam (PF20421)	Homo sapiens (human)
3	C, F (C, F)	Ras-related C3 botulinum toxin substrate 1	polymer	184	20244.3	2	UniProt (P63000) Pfam (PF00071)	Homo sapiens (human)	Cell migration-inducing gene 5 protein,Ras-like protein TC25,p21-Rac1

Sequence modifications

A, D: 1 - 727 (UniProt: Q92556)

PDB	External Database	Details
Gly -5	-	expression tag
Gly -4	-	expression tag
Ser -3	-	expression tag
Gly -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

B, E: 1 - 1642 (UniProt: Q9H7D0)

PDB	External Database	Details
Gly -5	-	expression tag
Gly -4	-	expression tag
Ser -3	-	expression tag
Gly -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag
Arg 1285	Lys 1285	variant

C, F: 1 - 177 (UniProt: P63000)

PDB	External Database	Details
Gly -6	-	expression tag
Ser -5	-	expression tag
Ser -4	-	expression tag
Gly -3	-	expression tag
Ser -2	-	expression tag
Ser -1	-	expression tag
Gly 0	-	expression tag
Ala 15	Gly 15	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	592148.2
All*	Total formula weight	592148.2

*Water molecules are not included.