8ZJ4
trypsinogen-EP-N619A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (D) | Enteropeptidase catalytic light chain | polymer | 235 | 26150.7 | 1 | UniProt (P98073) Pfam (PF00089) | Homo sapiens (human) | |
| 2 | B (C) | Serine protease 1 | polymer | 232 | 25042.1 | 1 | UniProt (P07477) Pfam (PF00089) | Homo sapiens (human) | Anionic trypsin I,Anionic trypsin-I,Beta-trypsin,Cationic trypsinogen,Pretrypsinogen I,Trypsin I,Trypsin-1 |
| 3 | C (A) | Enteropeptidase non-catalytic heavy chain | polymer | 603 | 66723.0 | 1 | UniProt (P98073) Pfam (PF00057) Pfam (PF00431) Pfam (PF00629) Pfam (PF15494) | Homo sapiens (human) | |
| 4 | D, J (B, J) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 2 | In PDB GlyTouCan (G15407YE) | |||
| 5 | E, G, M (E, G, M) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 3 | In PDB GlyTouCan (G62916OK) | |||
| 6 | F (F) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 7 | H (H) | alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G22573RC) | |||
| 8 | I (I) | beta-D-mannopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB | |||
| 9 | K (K) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G81315DD) | |||
| 10 | L (L) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB | |||
| 11 | N, O, P (D, A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) |
Sequence modifications
D: 785 - 1019 (UniProt: P98073)
A: 182 - 784 (UniProt: P98073)
| PDB | External Database | Details |
|---|---|---|
| Ala 825 | His 825 | engineered mutation |
| Ala 876 | Asp 876 | engineered mutation |
| Ala 971 | Ser 971 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Ala 619 | Asn 619 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 117915.8 | |
| Branched | Number of molecules | 10 |
| Total formula weight | 6189.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 663.6 | |
| All* | Total formula weight | 124769.1 |
