8ZHC
pre-frameshift complex of yeast 80S ribosome with eRF1 and mRNA of WNV
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (LA) | 25S rRNA (3393-MER) | polymer | 3393 | 1096497.3 | 1 | GenBank (1262303) | Saccharomyces cerevisiae S288C | |
| 2 | B (LB) | 5S rRNA (121-MER) | polymer | 121 | 38951.1 | 1 | GenBank (834774822) | Saccharomyces cerevisiae S288C | |
| 3 | C (LC) | 5.8S rRNA (158-MER) | polymer | 158 | 50682.9 | 1 | GenBank (1531397035) | Saccharomyces cerevisiae S288C | |
| 4 | D (LD) | Large ribosomal subunit protein uL2A | polymer | 251 | 27089.2 | 1 | UniProt (P0CX45) Pfam (PF00181) Pfam (PF03947) | Saccharomyces cerevisiae S288C | 60S ribosomal protein L2-A,L5,RP8,YL6 |
| 5 | E (LE) | Large ribosomal subunit protein uL3 | polymer | 386 | 43719.6 | 1 | UniProt (P14126) Pfam (PF00297) | Saccharomyces cerevisiae S288C | 60S ribosomal protein L3,Maintenance of killer protein 8,RP1,Trichodermin resistance protein,YL1 |
| 6 | F (LF) | Large ribosomal subunit protein uL4A | polymer | 361 | 39027.9 | 1 | UniProt (P10664) Pfam (PF00573) Pfam (PF14374) | Saccharomyces cerevisiae S288C | 60S ribosomal protein L4-A,L2,RP2,YL2 |
| 7 | G (LG) | Large ribosomal subunit protein uL18 | polymer | 294 | 33415.4 | 1 | UniProt (P26321) Pfam (PF17144) Pfam (PF14204) | Saccharomyces cerevisiae S288C | 60S ribosomal protein L5,L1,L1a,Ribosomal 5S RNA-binding protein,YL3 |
| 8 | H (LH) | Large ribosomal subunit protein eL6B | polymer | 175 | 19893.3 | 1 | UniProt (P05739) Pfam (PF01159) | Saccharomyces cerevisiae S288C | 60S ribosomal protein L6-B,L17,RP18,YL16 |
| 9 | I (LI) | Large ribosomal subunit protein uL30A | polymer | 222 | 25240.4 | 1 | UniProt (P05737) Pfam (PF00327) Pfam (PF08079) | Saccharomyces cerevisiae S288C | 60S ribosomal protein L7-A,L6,RP11,YL8 |
| 10 | J (LJ) | Large ribosomal subunit protein eL8A | polymer | 233 | 25815.0 | 1 | UniProt (P17076) Pfam (PF01248) | Saccharomyces cerevisiae S288C | 60S ribosomal protein L8-A,L4,L4-2,L7a-1,Maintenance of killer protein 7,RP6,YL5 |
| 11 | K (LK) | Large ribosomal subunit protein uL6A | polymer | 191 | 21605.1 | 1 | UniProt (P05738) Pfam (PF00347) | Saccharomyces cerevisiae S288C | 60S ribosomal protein L9-A,L8,RP24,YL11 |
| 12 | L (LL) | Large ribosomal subunit protein uL16 | polymer | 218 | 25080.1 | 1 | UniProt (P41805) Pfam (PF00252) | Saccharomyces cerevisiae S288C | 60S ribosomal protein L10,L9,Ubiquinol-cytochrome C reductase complex subunit VI-requiring protein |
| 13 | M (LM) | Large ribosomal subunit protein uL5B | polymer | 169 | 19266.1 | 1 | UniProt (Q3E757) Pfam (PF00281) Pfam (PF00673) | Saccharomyces cerevisiae S288C | 60S ribosomal protein L11-B,L16,RP39,YL22 |
| 14 | N (LN) | Large ribosomal subunit protein eL13A | polymer | 193 | 21885.2 | 1 | UniProt (Q12690) Pfam (PF01294) | Saccharomyces cerevisiae S288C | 60S ribosomal protein L13-A |
| 15 | O (LO) | Large ribosomal subunit protein eL14A | polymer | 136 | 14976.8 | 1 | UniProt (P36105) Pfam (PF00467) Pfam (PF01929) | Saccharomyces cerevisiae S288C | 60S ribosomal protein L14-A |
| 16 | P (LP) | Large ribosomal subunit protein eL15A | polymer | 203 | 24351.2 | 1 | UniProt (P05748) Pfam (PF00827) | Saccharomyces cerevisiae S288C | 60S ribosomal protein L15-A,L13,RP15R,YL10,YP18 |
| 17 | Q (LQ) | Large ribosomal subunit protein uL13A | polymer | 197 | 22029.0 | 1 | UniProt (P26784) Pfam (PF00572) | Saccharomyces cerevisiae S288C | 60S ribosomal protein L16-A,L13a,L21,RP22,YL15 |
| 18 | R (LR) | Large ribosomal subunit protein uL22A | polymer | 183 | 20458.3 | 1 | UniProt (P05740) Pfam (PF00237) | Saccharomyces cerevisiae S288C | 60S ribosomal protein L17-A,L20A,YL17 |
| 19 | S (LS) | Large ribosomal subunit protein eL18A | polymer | 185 | 20478.1 | 1 | UniProt (P0CX49) Pfam (PF17135) | Saccharomyces cerevisiae S288C | 60S ribosomal protein L18-A,RP28 |
| 20 | T (LT) | Large ribosomal subunit protein eL19A | polymer | 188 | 21631.1 | 1 | UniProt (P0CX82) Pfam (PF01280) | Saccharomyces cerevisiae S288C | 60S ribosomal protein L19-A,L23,RP15L,RP33,YL14 |
| 21 | U (LU) | Large ribosomal subunit protein eL20A | polymer | 171 | 20347.7 | 1 | UniProt (P0CX23) Pfam (PF01775) | Saccharomyces cerevisiae S288C | 60S ribosomal protein L20-A,L18a |
| 22 | V (LV) | Large ribosomal subunit protein eL21A | polymer | 159 | 18148.1 | 1 | UniProt (Q02753) Pfam (PF01157) | Saccharomyces cerevisiae S288C | 60S ribosomal protein L21-A |
| 23 | W (LW) | Large ribosomal subunit protein eL22A | polymer | 100 | 11263.9 | 1 | UniProt (P05749) Pfam (PF01776) | Saccharomyces cerevisiae S288C | 60S ribosomal protein L22-A,L1c,RP4,YL31 |
| 24 | X (LX) | Large ribosomal subunit protein uL14A | polymer | 136 | 14362.8 | 1 | UniProt (P0CX41) Pfam (PF00238) | Saccharomyces cerevisiae S288C | 60S ribosomal protein L23-A,L17a,YL32 |
| 25 | Y (LY) | Large ribosomal subunit protein eL24A | polymer | 65 | 7614.9 | 1 | UniProt (P04449) Pfam (PF01246) | Saccharomyces cerevisiae S288C | 60S ribosomal protein L24-A,L30,RP29,YL21 |
| 26 | Z (LZ) | Large ribosomal subunit protein uL23 | polymer | 121 | 13771.2 | 1 | UniProt (P04456) Pfam (PF03939) Pfam (PF00276) | Saccharomyces cerevisiae S288C | 60S ribosomal protein L25,RP16L,YL25,YP42' |
| 27 | AA (La) | Large ribosomal subunit protein uL24A | polymer | 125 | 14005.5 | 1 | UniProt (P05743) Pfam (PF16906) Pfam (PF00467) | Saccharomyces cerevisiae S288C | 60S ribosomal protein L26-A,L33,YL33 |
| 28 | BA (Lb) | Large ribosomal subunit protein eL27A | polymer | 135 | 15437.2 | 1 | UniProt (P0C2H6) Pfam (PF01777) | Saccharomyces cerevisiae S288C | 60S ribosomal protein L27-A |
| 29 | CA (Lc) | Large ribosomal subunit protein uL15 | polymer | 148 | 16630.5 | 1 | UniProt (P02406) Pfam (PF00828) | Saccharomyces cerevisiae S288C | 60S ribosomal protein L28,L27a,L29,RP44,RP62,YL24 |
| 30 | DA (Ld) | Large ribosomal subunit protein eL29 | polymer | 58 | 6560.7 | 1 | UniProt (P05747) Pfam (PF01779) | Saccharomyces cerevisiae S288C | 60S ribosomal protein L29,YL43 |
| 31 | EA (Le) | Large ribosomal subunit protein eL30 | polymer | 96 | 10487.3 | 1 | UniProt (P14120) Pfam (PF01248) | Saccharomyces cerevisiae S288C | 60S ribosomal protein L30,L32,RP73,YL38 |
| 32 | FA (Lf) | Large ribosomal subunit protein eL31A | polymer | 109 | 12649.8 | 1 | UniProt (P0C2H8) Pfam (PF01198) | Saccharomyces cerevisiae S288C | 60S ribosomal protein L31-A,L34,YL28 |
| 33 | GA (Lg) | Large ribosomal subunit protein eL32 | polymer | 127 | 14478.1 | 1 | UniProt (P38061) Pfam (PF01655) | Saccharomyces cerevisiae S288C | 60S ribosomal protein L32 |
| 34 | HA (Lh) | Large ribosomal subunit protein eL33A | polymer | 106 | 12045.9 | 1 | UniProt (P05744) Pfam (PF01247) | Saccharomyces cerevisiae S288C | 60S ribosomal protein L33-A,L37,RP47,YL37 |
| 35 | IA (Li) | Large ribosomal subunit protein eL34A | polymer | 112 | 12608.8 | 1 | UniProt (P87262) Pfam (PF01199) | Saccharomyces cerevisiae S288C | 60S ribosomal protein L34-A |
| 36 | JA (Lj) | Large ribosomal subunit protein uL29A | polymer | 119 | 13811.4 | 1 | UniProt (P0CX84) Pfam (PF00831) | Saccharomyces cerevisiae S288C | 60S ribosomal protein L35-A |
| 37 | KA (Lk) | Large ribosomal subunit protein eL36A | polymer | 99 | 11020.1 | 1 | UniProt (P05745) Pfam (PF01158) | Saccharomyces cerevisiae S288C | 60S ribosomal protein L36-A,L39,YL39 |
| 38 | LA (Ll) | Large ribosomal subunit protein eL37A | polymer | 81 | 9229.6 | 1 | UniProt (P49166) Pfam (PF01907) | Saccharomyces cerevisiae S288C | 60S ribosomal protein L37-A,L43,YL35,YP55 |
| 39 | MA (Lm) | Large ribosomal subunit protein eL38 | polymer | 77 | 8714.4 | 1 | UniProt (P49167) Pfam (PF01781) | Saccharomyces cerevisiae S288C | 60S ribosomal protein L38 |
| 40 | NA (Ln) | Large ribosomal subunit protein eL39 | polymer | 50 | 6227.4 | 1 | UniProt (P04650) Pfam (PF00832) | Saccharomyces cerevisiae S288C | 60S ribosomal protein L39,L46,YL40 |
| 41 | OA (Lo) | Large ribosomal subunit protein eL40A | polymer | 52 | 6032.3 | 1 | UniProt (P0CH08) Pfam (PF01020) | Saccharomyces cerevisiae S288C | 60S ribosomal protein L40-A,CEP52 |
| 42 | PA (Lp) | Large ribosomal subunit protein eL41A | polymer | 25 | 3354.2 | 1 | UniProt (P0CX86) Pfam (PF05162) | Saccharomyces cerevisiae S288C | 60S ribosomal protein L41-A,L47,YL41 |
| 43 | QA (Lq) | Large ribosomal subunit protein eL42A | polymer | 103 | 11840.2 | 1 | UniProt (P0CX27) Pfam (PF00935) | Saccharomyces cerevisiae S288C | 60S ribosomal protein L42-A,L41,YL27,YP44 |
| 44 | RA (Lr) | Large ribosomal subunit protein eL43A | polymer | 91 | 9981.8 | 1 | UniProt (P0CX25) Pfam (PF01780) | Saccharomyces cerevisiae S288C | 60S ribosomal protein L43-A,L37a,YL35 |
| 45 | SA (S2) | chain 2 18S rRNA (1799-MER) | polymer | 1799 | 579432.8 | 1 | GenBank (831416138) | Saccharomyces cerevisiae S288C | |
| 46 | TA (SA) | Small ribosomal subunit protein uS3 | polymer | 223 | 24702.8 | 1 | UniProt (P05750) Pfam (PF07650) Pfam (PF00189) | Saccharomyces cerevisiae S288C | 40S ribosomal protein S3,RP13,YS3 |
| 47 | UA (SB) | Small ribosomal subunit protein uS7 | polymer | 206 | 22908.3 | 1 | UniProt (P26783) Pfam (PF00177) | Saccharomyces cerevisiae S288C | 40S ribosomal protein S5,RP14,S2,YS8 |
| 48 | VA (SC) | Small ribosomal subunit protein eS10A | polymer | 92 | 11042.6 | 1 | UniProt (Q08745) Pfam (PF03501) | Saccharomyces cerevisiae S288C | 40S ribosomal protein S10-A |
| 49 | WA (SD) | Small ribosomal subunit protein eS12 | polymer | 124 | 13327.3 | 1 | UniProt (P48589) Pfam (PF01248) | Saccharomyces cerevisiae S288C | 40S ribosomal protein S12 |
| 50 | XA (SE) | Small ribosomal subunit protein uS19 | polymer | 117 | 13265.6 | 1 | UniProt (Q01855) Pfam (PF00203) | Saccharomyces cerevisiae S288C | 40S ribosomal protein S15,RIG protein,RP52,S21,YS21 |
| 51 | YA (SF) | Small ribosomal subunit protein uS9A | polymer | 141 | 15659.2 | 1 | UniProt (P0CX51) Pfam (PF00380) | Saccharomyces cerevisiae S288C | 40S ribosomal protein S16-A,RP61R |
| 52 | ZA (SG) | Small ribosomal subunit protein eS17A | polymer | 125 | 14268.5 | 1 | UniProt (P02407) Pfam (PF00833) | Saccharomyces cerevisiae S288C | 40S ribosomal protein S17-A,RP51A |
| 53 | AB (SH) | Small ribosomal subunit protein uS13A | polymer | 145 | 16940.4 | 1 | UniProt (P0CX55) Pfam (PF00416) | Saccharomyces cerevisiae S288C | 40S ribosomal protein S18-A |
| 54 | BB (SI) | Small ribosomal subunit protein eS19A | polymer | 143 | 15810.9 | 1 | UniProt (P07280) Pfam (PF01090) | Saccharomyces cerevisiae S288C | 40S ribosomal protein S19-A,RP55A,S16a,YP45,YS16A |
| 55 | CB (SJ) | Small ribosomal subunit protein uS10 | polymer | 101 | 11476.5 | 1 | UniProt (P38701) Pfam (PF00338) | Saccharomyces cerevisiae S288C | 40S ribosomal protein S20 |
| 56 | DB (SK) | Small ribosomal subunit protein eS25A | polymer | 82 | 9540.3 | 1 | UniProt (Q3E792) Pfam (PF03297) | Saccharomyces cerevisiae S288C | 40S ribosomal protein S25-A,RP45,S31,YS23 |
| 57 | EB (SL) | Small ribosomal subunit protein eS28A | polymer | 63 | 7116.3 | 1 | UniProt (Q3E7X9) Pfam (PF01200) | Saccharomyces cerevisiae S288C | 40S ribosomal protein S28-A,S33,YS27 |
| 58 | FB (SM) | Small ribosomal subunit protein uS14A | polymer | 53 | 6335.3 | 1 | UniProt (P41057) Pfam (PF00253) | Saccharomyces cerevisiae S288C | 40S ribosomal protein S29-A,S36,YS29 |
| 59 | GB (SN) | Small ribosomal subunit protein eS31 | polymer | 73 | 8388.0 | 1 | UniProt (P05759) Pfam (PF01599) | Saccharomyces cerevisiae S288C | 40S ribosomal protein S31,CEP76,S37,YS24 |
| 60 | HB (SO) | Small ribosomal subunit protein RACK1 | polymer | 312 | 34151.5 | 1 | UniProt (P38011) Pfam (PF00400) | Saccharomyces cerevisiae S288C | Guanine nucleotide-binding protein subunit beta-like protein,Receptor for activated C kinase,Receptor of activated protein kinase C 1,RACK1 |
| 61 | IB (SP) | Small ribosomal subunit protein uS2A | polymer | 206 | 22811.1 | 1 | UniProt (P32905) Pfam (PF00318) | Saccharomyces cerevisiae S288C | 40S ribosomal protein S0-A,Nucleic acid-binding protein NAB1A |
| 62 | JB (SQ) | Small ribosomal subunit protein eS1A | polymer | 232 | 26314.7 | 1 | UniProt (P33442) Pfam (PF01015) | Saccharomyces cerevisiae S288C | 40S ribosomal protein S1-A,RP10A |
| 63 | KB (SR) | Small ribosomal subunit protein uS5 | polymer | 217 | 23213.0 | 1 | UniProt (P25443) Pfam (PF00333) Pfam (PF03719) | Saccharomyces cerevisiae S288C | 40S ribosomal protein S2,Omnipotent suppressor protein SUP44,RP12,S4,YS5 |
| 64 | LB (SS) | Small ribosomal subunit protein eS4A | polymer | 260 | 29338.1 | 1 | UniProt (P0CX35) Pfam (PF08071) Pfam (PF01479) Pfam (PF00900) Pfam (PF00467) Pfam (PF16121) | Saccharomyces cerevisiae S288C | 40S ribosomal protein S4-A,RP5,S7,YS6 |
| 65 | MB (ST) | Small ribosomal subunit protein eS6A | polymer | 228 | 26181.4 | 1 | UniProt (P0CX37) Pfam (PF01092) | Saccharomyces cerevisiae S288C | 40S ribosomal protein S6-A,RP9,S10,YS4 |
| 66 | NB (SU) | Small ribosomal subunit protein eS7A | polymer | 185 | 21071.6 | 1 | UniProt (P26786) Pfam (PF01251) | Saccharomyces cerevisiae S288C | 40S ribosomal protein S7-A,RP30,RP40 |
| 67 | OB (SV) | Small ribosomal subunit protein eS8A | polymer | 199 | 22406.6 | 1 | UniProt (P0CX39) Pfam (PF01201) | Saccharomyces cerevisiae S288C | 40S ribosomal protein S8-A,RP19,S14,YS9 |
| 68 | PB (SW) | Small ribosomal subunit protein uS4A | polymer | 185 | 21210.7 | 1 | UniProt (O13516) Pfam (PF00163) Pfam (PF01479) | Saccharomyces cerevisiae S288C | 40S ribosomal protein S9-A,RP21,S13,YP28,YS11 |
| 69 | QB (SX) | Small ribosomal subunit protein uS17A | polymer | 146 | 16588.5 | 1 | UniProt (P0CX47) Pfam (PF16205) Pfam (PF00366) | Saccharomyces cerevisiae S288C | 40S ribosomal protein S11-A,RP41,S18,YS12 |
| 70 | RB (SY) | Small ribosomal subunit protein uS15 | polymer | 150 | 16928.7 | 1 | UniProt (P05756) Pfam (PF08069) Pfam (PF00312) | Saccharomyces cerevisiae S288C | 40S ribosomal protein S13,S27a,YS15 |
| 71 | SB (SZ) | Small ribosomal subunit protein uS11B | polymer | 128 | 13560.5 | 1 | UniProt (P39516) Pfam (PF00411) | Saccharomyces cerevisiae S288C | 40S ribosomal protein S14-B,RP59B |
| 72 | TB (Sa) | Small ribosomal subunit protein eS21A | polymer | 87 | 9758.8 | 1 | UniProt (P0C0V8) Pfam (PF01249) | Saccharomyces cerevisiae S288C | 40S ribosomal protein S21-A,S26,YS25 |
| 73 | UB (Sb) | Small ribosomal subunit protein uS8A | polymer | 129 | 14518.9 | 1 | UniProt (P0C0W1) Pfam (PF00410) | Saccharomyces cerevisiae S288C | 40S ribosomal protein S22-A,RP50,S24,YP58,YS22 |
| 74 | VB (Sc) | Small ribosomal subunit protein uS12A | polymer | 144 | 15942.7 | 1 | UniProt (P0CX29) Pfam (PF00164) | Saccharomyces cerevisiae S288C | 40S ribosomal protein S23-A,RP37,S28,YS14 |
| 75 | WB (Sd) | Small ribosomal subunit protein eS24A | polymer | 134 | 15231.6 | 1 | UniProt (P0CX31) Pfam (PF01282) | Saccharomyces cerevisiae S288C | 40S ribosomal protein S24-A,RP50 |
| 76 | XB (Se) | Small ribosomal subunit protein eS26B | polymer | 97 | 11023.0 | 1 | UniProt (P39939) Pfam (PF01283) | Saccharomyces cerevisiae S288C | 40S ribosomal protein S26-B |
| 77 | YB (Sf) | Small ribosomal subunit protein eS27A | polymer | 81 | 8762.2 | 1 | UniProt (P35997) Pfam (PF01667) | Saccharomyces cerevisiae S288C | 40S ribosomal protein S27-A,RP61,YS20 |
| 78 | ZB (Sg) | Small ribosomal subunit protein eS30A | polymer | 57 | 6479.7 | 1 | UniProt (P0CX33) Pfam (PF04758) | Saccharomyces cerevisiae S288C | 40S ribosomal protein S30-A |
| 79 | AC (Ta) | tRNA (77-MER) | polymer | 77 | 24880.9 | 1 | Saccharomyces cerevisiae S288C | ||
| 80 | BC (eR) | Eukaryotic peptide chain release factor subunit 1 | polymer | 446 | 50225.0 | 1 | UniProt (P62495) Pfam (PF03463) Pfam (PF03464) Pfam (PF03465) | Homo sapiens (human) | Eukaryotic release factor 1,eRF1,Protein Cl1,TB3-1 |
| 81 | CC (mR) | RNA (5'-R(P*GP*AP*CP*CP*CP*UP*UP*AP*AP*C)-3') | polymer | 25 | 7975.8 | 1 | West Nile virus | ||
| 82 | DC (pp) | Peptide 2k | polymer | 32 | 3813.3 | 1 | UniProt (P06935) | West Nile virus |
Sequence modifications
LA: 3 - 3395 (GenBank: 1262303)
eR: 1 - 437 (UniProt: P62495)
pp: 4353 - 4384 (UniProt: P06935)
| PDB | External Database | Details |
|---|---|---|
| - | G 25080 | deletion |
| PDB | External Database | Details |
|---|---|---|
| Met -8 | - | initiating methionine |
| His -7 | - | expression tag |
| His -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Ala 183 | Gly 183 | conflict |
| Ala 184 | Gly 184 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Gln 4362 | Thr 1125 | conflict |
| Gln 4373 | Arg 1136 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 82 |
| Total formula weight | 3105319.5 | |
| All* | Total formula weight | 3105319.5 |
