8ZH4
HIV-1 integrase core domain in complex with compound 5
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Integrase | polymer | 166 | 18443.7 | 1 | UniProt (P12497) Pfam (PF00665) In PDB | Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE) | IN |
| 2 | A | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
| 3 | A | (2~{S})-2-(4',5-dimethylspiro[1,2-dihydroindene-3,1'-cyclohexane]-4-yl)-2-[(2-methylpropan-2-yl)oxy]ethanoic acid | non-polymer | 344.5 | 1 | Chemie (A1L1V) | |||
| 4 | A | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 5 | water | water | 18.0 | 84 | Chemie (HOH) |
Sequence modifications
A: 50 - 212 (UniProt: P12497)
| PDB | External Database | Details |
|---|---|---|
| Gly 47 | - | expression tag |
| Ser 48 | - | expression tag |
| His 49 | - | expression tag |
| His 185 | Phe 1332 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 18443.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 730.8 | |
| All* | Total formula weight | 19174.5 |
