8ZGS
Structure of the ige-fc bound to its high affinity receptor fc(epsilon)ri state2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | High affinity immunoglobulin epsilon receptor subunit alpha | polymer | 245 | 27830.2 | 1 | UniProt (P12371) Pfam (PF13895) | Rattus norvegicus (Norway rat) | Fc-epsilon RI-alpha,FcERI,IgE Fc receptor subunit alpha |
| 2 | B (B) | High affinity immunoglobulin epsilon receptor subunit beta | polymer | 243 | 26747.8 | 1 | UniProt (P13386) Pfam (PF04103) | Rattus norvegicus (Norway rat) | FcERI,Fc epsilon receptor I beta-chain,IgE Fc receptor subunit beta |
| 3 | C, F (C, G) | High affinity immunoglobulin epsilon receptor subunit gamma | polymer | 86 | 9774.5 | 2 | UniProt (P20411) Pfam (PF11628) Pfam (PF02189) | Rattus norvegicus (Norway rat) | Fc receptor gamma-chain,FcRgamma,Fc-epsilon RI-gamma,IgE Fc receptor subunit gamma,FceRI gamma |
| 4 | D, E (E, F) | Immunoglobulin heavy constant epsilon | polymer | 374 | 43155.8 | 2 | UniProt (P01855) Pfam (PF07654) Pfam (PF00047) | Rattus norvegicus (Norway rat) | Ig epsilon chain C region |
| 5 | G (T) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 6 | H, I (D, H) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 2 | In PDB GlyTouCan (G15407YE) | |||
| 7 | J, K, M, N, O (A, E, F) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 5 | Chemie (NAG) | |||
| 8 | L (B) | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 1 | Chemie (Y01) PubChem (16219150) PubChem (22210610) PubChem (65082) PubChem (363416) PubChem (45489984) PubChem (500055) PubChem (60078761) PubChem (57163942) PubChem (73440805) PubChem (89891013) PubChem (13301926) PubChem (13301927) PubChem (99567469) PubChem (99567468) PubChem (124427194) PubChem (124897021) PubChem (124897020) PubChem (10005657) PubChem (130340716) PubChem (11969853) PubChem (124301053) PubChem (124302591) PubChem (124303794) PubChem (124421343) PubChem (124427195) PubChem (137392566) PubChem (137496323) PubChem (124914595) PubChem (124914596) PubChem (131705526) PubChem (155804219) PubChem (137332121) PubChem (137496357) PubChem (146157332) PubChem (169132514) PubChem (154929912) PubChem (155199678) PubChem (156327905) PubChem (156426247) PubChem (156516588) PubChem (166979870) PubChem (167024614) PubChem (169132513) PubChem (170117245) PubChem (172400028) |
Sequence modifications
E, F: 95 - 429 (UniProt: P01855)
| PDB | External Database | Details |
|---|---|---|
| Met 73 | - | initiating methionine |
| Ser 74 | - | expression tag |
| Val 75 | - | expression tag |
| Pro 76 | - | expression tag |
| Thr 77 | - | expression tag |
| Gln 78 | - | expression tag |
| Val 79 | - | expression tag |
| Leu 80 | - | expression tag |
| Gly 81 | - | expression tag |
| Leu 82 | - | expression tag |
| Leu 83 | - | expression tag |
| Leu 84 | - | expression tag |
| Leu 85 | - | expression tag |
| Trp 86 | - | expression tag |
| Leu 87 | - | expression tag |
| Thr 88 | - | expression tag |
| Asp 89 | - | expression tag |
| Ala 90 | - | expression tag |
| Arg 91 | - | expression tag |
| Cys 92 | - | expression tag |
| Asp 93 | - | expression tag |
| Ile 94 | - | expression tag |
| His 430 | - | expression tag |
| His 431 | - | expression tag |
| His 432 | - | expression tag |
| His 433 | - | expression tag |
| His 434 | - | expression tag |
| His 435 | - | expression tag |
| Ser 436 | - | expression tag |
| Arg 437 | - | expression tag |
| Val 438 | - | expression tag |
| Asp 439 | - | expression tag |
| Tyr 440 | - | expression tag |
| Lys 441 | - | expression tag |
| Asp 442 | - | expression tag |
| Asp 443 | - | expression tag |
| Asp 444 | - | expression tag |
| Asp 445 | - | expression tag |
| Lys 446 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 160438.5 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 1597.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1592.8 | |
| All* | Total formula weight | 163628.8 |
