8ZFP

Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with GW9662 and MRL24

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Peroxisome proliferator-activated receptor gamma	polymer	275	31449.5	2	UniProt (P37231) Pfam (PF00104) In PDB	Homo sapiens (human)	PPAR-gamma,Nuclear receptor subfamily 1 group C member 3
2	A, B	2-chloro-5-nitro-N-phenylbenzamide	non-polymer		276.7	2	Chemie (GW9)
3	A, B	(2S)-2-(3-{[1-(4-METHOXYBENZOYL)-2-METHYL-5-(TRIFLUOROMETHOXY)-1H-INDOL-3-YL]METHYL}PHENOXY)PROPANOIC ACID	non-polymer		527.5	2	Chemie (241)
4		water	water		18.0	82	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	62899.0
Non-Polymers*	Number of molecules	4
	Total formula weight	1608.3
All*	Total formula weight	64507.4

*Water molecules are not included.