8ZFO
Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with GW9662 and nTZDpa
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B (A, B) | Peroxisome proliferator-activated receptor gamma | polymer | 275 | 31449.5 | 2 | UniProt (P37231) Pfam (PF00104) | Homo sapiens (human) | PPAR-gamma,Nuclear receptor subfamily 1 group C member 3 |
2 | C, E (A, B) | 5-CHLORO-1-(4-CHLOROBENZYL)-3-(PHENYLTHIO)-1H-INDOLE-2-CARBOXYLIC ACID | non-polymer | 428.3 | 2 | Chemie (NZA) | |||
3 | D (B) | 2-chloro-5-nitro-N-phenylbenzamide | non-polymer | 276.7 | 1 | Chemie (GW9) | |||
4 | F (B) | water | water | 18.0 | 2 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 62899.0 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 1133.3 | |
All* | Total formula weight | 64032.4 |