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8ZFO

Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with GW9662 and nTZDpa

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Peroxisome proliferator-activated receptor gammapolymer27531449.52UniProt (P37231)
Pfam (PF00104)
Homo sapiens (human)PPAR-gamma,Nuclear receptor subfamily 1 group C member 3
2C, E
(A, B)
5-CHLORO-1-(4-CHLOROBENZYL)-3-(PHENYLTHIO)-1H-INDOLE-2-CARBOXYLIC ACIDnon-polymer428.32Chemie (NZA)
3D
(B)
2-chloro-5-nitro-N-phenylbenzamidenon-polymer276.71Chemie (GW9)
4F
(B)
waterwater18.02Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight62899.0
Non-Polymers*Number of molecules3
Total formula weight1133.3
All*Total formula weight64032.4
*Water molecules are not included.

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PDB entries from 2024-11-13

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