8ZFK
Caenorhabditis elegans ACR-23 in betaine and monepantel bound state
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E (D, A, B, C, E) | Betaine receptor acr-23,Soluble cytochrome b562 | polymer | 620 | 70582.3 | 5 | UniProt (G5EG88) UniProt (P0ABE7) Pfam (PF02931) Pfam (PF02932) Pfam (PF07361) | Caenorhabditis elegans | Acetylcholine receptor subunit alpha-type acr-23,Cytochrome b-562 |
| 2 | F, G, H, I, J... (F, G, H, I, J...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 10 | In PDB GlyTouCan (G42666HT) | |||
| 3 | BA, P, S, V, Y (E, D, A, B, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 5 | Chemie (NAG) | |||
| 4 | CA, Q, T, W, Z (E, D, A, B, C) | ~{N}-[(2~{S})-2-cyano-1-[5-cyano-2-(trifluoromethyl)phenoxy]propan-2-yl]-4-(trifluoromethylsulfanyl)benzamide | non-polymer | 473.4 | 5 | Chemie (A1D8E) | |||
| 5 | AA, DA, R, U, X (C, E, D, A, B) | TRIMETHYL GLYCINE | non-polymer | 118.2 | 5 | Chemie (BET) | |||
| 6 | EA, FA, GA, HA, IA (D, A, B, C, E) | water | water | 18.0 | 15 | Chemie (HOH) |
Sequence modifications
D, A, B, C, E: 1 - 385 (UniProt: G5EG88)
D, A, B, C, E: 385 - 389 (UniProt: P0ABE7)
D, A, B, C, E: 389 - 534 (UniProt: G5EG88)
| PDB | External Database | Details |
|---|---|---|
| - | Ser 267 | deletion |
| - | Val 268 | deletion |
| - | Asn 269 | deletion |
| - | Pro 270 | deletion |
| - | Phe 271 | deletion |
| - | Thr 272 | deletion |
| - | Asn 273 | deletion |
| - | Phe 274 | deletion |
| - | Cys 275 | deletion |
| - | Asn 276 | deletion |
| - | Val 277 | deletion |
| PDB | External Database | Details |
|---|---|---|
| Trp 385 | Met 29 | conflict |
| Ile 389 | His 124 | conflict |
| Leu 389 | - | linker |
| Ser 389 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Met 385 | - | linker |
| Ala 385 | - | linker |
| Glu 385 | - | linker |
| Ala 385 | - | linker |
| Gly 385 | - | linker |
| Ala 385 | - | linker |
| Met 385 | - | linker |
| Leu 535 | - | expression tag |
| Glu 536 | - | expression tag |
| Gly 537 | - | expression tag |
| Thr 538 | - | expression tag |
| Lys 539 | - | expression tag |
| Leu 540 | - | expression tag |
| Val 541 | - | expression tag |
| Pro 542 | - | expression tag |
| Arg 543 | - | expression tag |
| Gly 544 | - | expression tag |
| Ser 545 | - | expression tag |
| Ser 546 | - | expression tag |
| Ser 547 | - | expression tag |
| Gly 548 | - | expression tag |
| Trp 549 | - | expression tag |
| Ser 550 | - | expression tag |
| His 551 | - | expression tag |
| Pro 552 | - | expression tag |
| Gln 553 | - | expression tag |
| Phe 554 | - | expression tag |
| Glu 555 | - | expression tag |
| Lys 556 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 352911.4 | |
| Branched | Number of molecules | 10 |
| Total formula weight | 4244.0 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 4063.8 | |
| All* | Total formula weight | 361219.2 |
