8ZDV
The cryoEM structure of H5N8 HA in an auto inhibited state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (B, A, C) | Hemagglutinin | polymer | 336 | 37793.0 | 3 | UniProt (A0A8E4ZAK5) | Influenza A virus | HA1 |
| 2 | D, E, F (G, H, I) | Hemagglutinin | polymer | 190 | 21995.5 | 3 | UniProt (A0A7S5LHD9) UniProt (by SIFTS) (A0A8K1DYS3) | Influenza A virus | HA2 |
| 3 | G, H, I (D, E, F) | N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1405.3 | 3 | In PDB GlyTouCan (G85526ZL) | |||
| 4 | J, K, L, M, N... (B, A, C, G, H...) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 12 | Chemie (NAG) PubChem (24139) |
Sequence modifications
B, A, C: -5 - 323 (UniProt: A0A8E4ZAK5)
G, H, I: -8 - 181 (UniProt: A0A7S5LHD9)
| PDB | External Database | Details |
|---|---|---|
| Ser 94 | Ala 102 | conflict |
| Gln 173 | Arg 185 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Gly 164 | Glu 493 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 179365.6 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 4215.8 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 2654.5 | |
| All* | Total formula weight | 186236.0 |
