8ZBW
Cryo-EM structure of formyl peptide receptor 2/C1R receptor in complex with Gi
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Guanine nucleotide-binding protein G(i) subunit alpha-2 | polymer | 351 | 40110.4 | 1 | UniProt (P04899) Pfam (PF00503) | Homo sapiens (human) | Adenylate cyclase-inhibiting G alpha protein |
| 2 | B (B) | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 338 | 37198.7 | 1 | UniProt (P62873) Pfam (PF00400) | Homo sapiens (human) | Transducin beta chain 1 |
| 3 | C (C) | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 53 | 5888.8 | 1 | UniProt (P59768) Pfam (PF00631) | Homo sapiens (human) | G gamma-I |
| 4 | D (R) | N-formyl peptide receptor 2 | polymer | 299 | 33398.3 | 1 | UniProt (P25090) Pfam (PF00001) | Homo sapiens (human) | FMLP-related receptor I,FMLP-R-I,Formyl peptide receptor-like 1,HM63,Lipoxin A4 receptor,LXA4 receptor,RFP |
| 5 | E (R) | C1R | non-polymer | 445.5 | 1 | Chemie (A1L1D) |
Sequence modifications
A: 5 - 355 (UniProt: P04899)
R: 19 - 317 (UniProt: P25090)
| PDB | External Database | Details |
|---|---|---|
| Asn 47 | Ser 47 | conflict |
| Ala 204 | Gly 204 | conflict |
| Ala 246 | Glu 246 | conflict |
| Ser 327 | Ala 327 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Leu 211 | Ser 211 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 116596.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 445.5 | |
| All* | Total formula weight | 117041.6 |
