8Z94

Cryo-EM structure of RIPK1 RHIM PFFs cross seeded RIPK3 RHIM amyloid fibril

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (B, A, C)	Receptor-interacting serine/threonine-protein kinase 3	polymer	141	15311.8	3	UniProt (Q9Y572) Pfam (PF12721)	Homo sapiens (human)	RIP-like protein kinase 3,Receptor-interacting protein 3,RIP-3

Sequence modifications

B, A, C: 388 - 518 (UniProt: Q9Y572)

PDB	External Database	Details
Met 386	-	initiating methionine
Gly 387	-	expression tag
Leu 519	-	expression tag
Glu 520	-	expression tag
His 521	-	expression tag
His 522	-	expression tag
His 523	-	expression tag
His 524	-	expression tag
His 525	-	expression tag
His 526	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	45935.3
All*	Total formula weight	45935.3

*Water molecules are not included.