8Z8Z

Cryo-EM structure of LYCHOS

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Lysosomal cholesterol signaling protein,Fluorescent Protein	polymer	1144	127213.1	2	UniProt (Q7Z3F1) Pfam (PF03547) Pfam (PF00610)	Homo sapiens (human)	LYCHOS,G-protein coupled receptor PGR22
2	C, L (A, B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG) PubChem (24139)
3	D, E, F, M, N... (A, B)	[(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate	non-polymer		718.0	6	Chemie (6OU)
4	G, P (A, B)	CHOLESTEROL	non-polymer		386.7	2	Chemie (CLR) PubChem (5997)
5	H, Q (A, B)	[(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (4~{Z},7~{Z},10~{Z},13~{Z},16~{Z},19~{Z})-docosa-4,7,10,13,16,19-hexaenoate	non-polymer		764.0	2	Chemie (A1L1C)
6	I, K (A, B)	1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine	non-polymer		760.1	2	Chemie (LBN)
7	J, R (A, B)	SODIUM ION	non-polymer		23.0	2	Chemie (NA) PubChem (923)
8	S, T (A, B)	water	water		18.0	2	Chemie (HOH)

Sequence modifications

A, B: 1 - 870 (UniProt: Q7Z3F1)

PDB	External Database	Details
Met -2	-	initiating methionine
Gly -1	-	expression tag
Ser 0	-	expression tag

A, B: 871 - 1141 (PDB: 8Z8Z)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	254426.2
Non-Polymers*	Number of molecules	16
	Total formula weight	8617.9
All*	Total formula weight	263044.1

*Water molecules are not included.