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8Z8Z

Cryo-EM structure of LYCHOS

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Lysosomal cholesterol signaling protein,Fluorescent Proteinpolymer1144127213.12UniProt (Q7Z3F1)
Pfam (PF03547)
Pfam (PF00610)
Homo sapiens (human)LYCHOS,G-protein coupled receptor PGR22
2C, L
(A, B)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.22Chemie (NAG)
3D, E, F, M, N...
(A, B)
[(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoatenon-polymer718.06Chemie (6OU)
4G, P
(A, B)
CHOLESTEROLnon-polymer386.72Chemie (CLR)
5H, Q
(A, B)
[(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (4~{Z},7~{Z},10~{Z},13~{Z},16~{Z},19~{Z})-docosa-4,7,10,13,16,19-hexaenoatenon-polymer764.02Chemie (A1L1C)
6I, K
(A, B)
1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholinenon-polymer760.12Chemie (LBN)
7J, R
(A, B)
SODIUM IONnon-polymer23.02Chemie (NA)
8S, T
(A, B)
waterwater18.02Chemie (HOH)
Sequence modifications
A, B: 1 - 870 (UniProt: Q7Z3F1)
PDBExternal DatabaseDetails
Met -2-initiating methionine
Gly -1-expression tag
Ser 0-expression tag
A, B: 871 - 1141 (PDB: 8Z8Z)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight254426.2
Non-Polymers*Number of molecules16
Total formula weight8617.9
All*Total formula weight263044.1
*Water molecules are not included.

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PDB entries from 2025-10-29

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