8Z7C

Structure of G9a in complex with compound 7i

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Histone-lysine N-methyltransferase EHMT2	polymer	283	32604.9	2	UniProt (Q96KQ7) Pfam (PF05033) Pfam (PF00856)	Homo sapiens (human)	Euchromatic histone-lysine N-methyltransferase 2,HLA-B-associated transcript 8,Histone H3-K9 methyltransferase 3,H3-K9-HMTase 3,Lysine N-methyltransferase 1C,Protein G9a
2	C, D, E, F, I... (A, B)	ZINC ION	non-polymer		65.4	8	Chemie (ZN)
3	G, M (A, B)	SINEFUNGIN	non-polymer		381.4	2	Chemie (SFG) PubChem (25246236) PubChem (46875078) PubChem (46936257) PubChem (176612030) PubChem (177116271) PubChem (65482) PubChem (70789212) PubChem (93287274) PubChem (70602121) PubChem (12771338) PubChem (92403972) PubChem (93287270) PubChem (93287272) PubChem (93475589) PubChem (456189) PubChem (4065234) PubChem (6917665) PubChem (131971033) PubChem (131972810) PubChem (138626357) PubChem (12771337) PubChem (156562738) PubChem (162866891) PubChem (163339130) PubChem (168280605)
4	H, N (A, B)	3,6,6-trimethyl-~{N}-[(2~{S})-1-[[4-(1-methylpiperidin-4-yl)oxyphenyl]amino]-1-oxidanylidene-hexan-2-yl]-4-oxidanylidene-5,7-dihydro-1~{H}-indole-2-carboxamide	non-polymer		522.7	2	Chemie (A1L07)
5	O, P (A, B)	water	water		18.0	626	Chemie (HOH)

Sequence modifications

A, B: 913 - 1193 (UniProt: Q96KQ7)

PDB	External Database	Details
Gly 911	-	expression tag
Ser 912	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	65209.8
Non-Polymers*	Number of molecules	12
	Total formula weight	2331.4
All*	Total formula weight	67541.3

*Water molecules are not included.