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8Z6O

Crystal structure of HDGFRP2 PWWP domain in complex with Varenicline

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Hepatoma-derived growth factor-related protein 2polymer9310657.22UniProt (Q7Z4V5)
Pfam (PF00855)
Homo sapiens (human)HDGF-related protein 2,HRP-2,Hepatoma-derived growth factor 2,HDGF-2
2C
(A)
DIMETHYL SULFOXIDEnon-polymer78.11Chemie (DMS)
3D
(B)
VARENICLINEnon-polymer211.31Chemie (QMR)
4E, F
(A, B)
waterwater18.0181Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight21314.4
Non-Polymers*Number of molecules2
Total formula weight289.4
All*Total formula weight21603.8
*Water molecules are not included.

250059

PDB entries from 2026-03-04

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