8Z5L
Crystal structure of metallo-beta-lactamse, IMP-1, complexed with a quinolinone-based inhibitor
This is a non-PDB format compatible entry.
Replaces: 8Y0SEntity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Metallo-beta-lactamase type 2 | polymer | 234 | 25685.3 | 4 | UniProt (P52699) Pfam (PF00753) In PDB | Serratia marcescens | B2 metallo-beta-lactamase,BLA-IMP,IMP-1,Beta-lactamase type II,Metallo-beta-lactamase type II |
2 | A, B, C, D | ZINC ION | non-polymer | 65.4 | 12 | Chemie (ZN) | |||
3 | B, C | 3-[2-azanyl-5-[2-cyclohexylethyl-[3-(4-methylphenoxy)propyl]amino]phenyl]propanoic acid | non-polymer | 438.6 | 2 | Chemie (A1LXO) | |||
4 | water | water | 18.0 | 71 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 6 - 232 (UniProt: P52699)
PDB | External Database | Details |
---|---|---|
Gly 1 | - | expression tag |
Pro 2 | - | expression tag |
Gly 3 | - | expression tag |
Val 4 | - | expression tag |
Gly 5 | - | expression tag |
Lys 233 | - | expression tag |
Leu 234 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 102741.4 | |
Non-Polymers* | Number of molecules | 14 |
Total formula weight | 1662.1 | |
All* | Total formula weight | 104403.5 |