8Z5L

Crystal structure of metallo-beta-lactamse, IMP-1, complexed with a quinolinone-based inhibitor

This is a non-PDB format compatible entry.

Replaces:  8Y0S

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Metallo-beta-lactamase type 2	polymer	234	25685.3	4	UniProt (P52699)	Serratia marcescens	B2 metallo-beta-lactamase,BLA-IMP,IMP-1,Beta-lactamase type II,Metallo-beta-lactamase type II
2	E, F, G, H, I... (A, B, C, D)	ZINC ION	non-polymer		65.4	12	Chemie (ZN)
3	K, O (B, C)	3-[2-azanyl-5-[2-cyclohexylethyl-[3-(4-methylphenoxy)propyl]amino]phenyl]propanoic acid	non-polymer		438.6	2	Chemie (A1LXO) PubChem (170459263)
4	S, T, U, V (A, B, C, D)	water	water		18.0	71	Chemie (HOH)

Sequence modifications

A, B, C, D: 6 - 232 (UniProt: P52699)

PDB	External Database	Details
Gly 1	-	expression tag
Pro 2	-	expression tag
Gly 3	-	expression tag
Val 4	-	expression tag
Gly 5	-	expression tag
Lys 233	-	expression tag
Leu 234	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	102741.4
Non-Polymers*	Number of molecules	14
	Total formula weight	1662.1
All*	Total formula weight	104403.5

*Water molecules are not included.