8Z5E
Crystal structure of beta-ketoacyl-ACP synthase FabF K336A in complex with octanoyl-ACP from Helicobacter pylori
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, D, E (A, B, D, E) | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | polymer | 413 | 43584.7 | 4 | UniProt (A0A438WLJ1) UniProt (by SIFTS) (V6LC02) | Helicobacter pylori (Campylobacter pylori) | |
| 2 | C, F (C, F) | Acyl carrier protein | polymer | 86 | 9363.5 | 2 | UniProt (Q5EDC8) | Helicobacter pylori (Campylobacter pylori) | ACP |
| 3 | G, H, J, K (A, B, D, E) | OCTANOIC ACID (CAPRYLIC ACID) | non-polymer | 144.2 | 4 | Chemie (OCA) | Helicobacter pylori | ||
| 4 | I, L (C, F) | N~3~-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-N-(2-sulfanylethyl)-beta-alaninamide | non-polymer | 358.3 | 2 | Chemie (PN7) | Helicobacter pylori | ||
| 5 | M, N, O, P, Q... (A, B, C, D, E...) | water | water | 18.0 | 799 | Chemie (HOH) |
Sequence modifications
A, B, D, E: 1 - 412 (UniProt: A0A438WLJ1)
C, F: 1 - 78 (UniProt: Q5EDC8)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
| Ala 336 | Lys 336 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly -7 | - | expression tag |
| Thr -6 | - | expression tag |
| Ser -5 | - | expression tag |
| Ser -4 | - | expression tag |
| Met -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Tyr -1 | - | expression tag |
| Leu 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 193065.8 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1293.5 | |
| All* | Total formula weight | 194359.3 |
