8Z3S
Activation mechanism and novel binding site of the BKCa channel activator CTIBD
This is a non-PDB format compatible entry.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D (A, B, C, D) | Calcium-activated potassium channel subunit alpha-1 | polymer | 1114 | 125541.5 | 4 | UniProt (Q12791) Pfam (PF00520) Pfam (PF07885) Pfam (PF22614) Pfam (PF03493) Pfam (PF21014) | Homo sapiens (human) | BK channel,BKCA alpha,Calcium-activated potassium channel,subfamily M subunit alpha-1,K(VCA)alpha,KCa1.1,Maxi K channel,MaxiK,Slo-alpha,Slo1,Slowpoke homolog,Slo homolog,hSlo |
2 | E, F, K, L, Q... (A, B, C, D) | 4-[4-(4-chlorophenyl)-3-(trifluoromethyl)-1,2-oxazol-5-yl]benzene-1,3-diol | non-polymer | 355.7 | 8 | Chemie (A1L04) | |||
3 | G, M, S, Y (A, B, C, D) | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 4 | Chemie (Y01) | |||
4 | H, N, T, Z (A, B, C, D) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
5 | AA, BA, I, J, O... (D, A, B, C) | CALCIUM ION | non-polymer | 40.1 | 8 | Chemie (CA) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 502165.8 | |
Non-Polymers* | Number of molecules | 24 |
Total formula weight | 5210.3 | |
All* | Total formula weight | 507376.2 |