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8Z1L

Cryo-EM structure of human norepinephrine transporter NET in the presence of the antidepressant atomoxetine in an outward-open state at resolution of 3.4 angstrom.

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Sodium-dependent noradrenaline transporterpolymer61769386.51UniProt (P23975)
Pfam (PF00209)
Homo sapiens (human)Norepinephrine transporter,NET,Solute carrier family 6 member 2
2B
(A)
CHLORIDE IONnon-polymer35.51Chemie (CL)
3C
(A)
(3R)-N-methyl-3-(2-methylphenoxy)-3-phenyl-propan-1-aminenon-polymer255.41Chemie (A1LX4)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight69386.5
Non-Polymers*Number of molecules2
Total formula weight290.8
All*Total formula weight69677.4
*Water molecules are not included.

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PDB entries from 2024-11-13

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