8Z0T
Structure of the human ige-fc bound to its high affinity receptor fc(epsilon)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | High affinity immunoglobulin epsilon receptor subunit alpha | polymer | 257 | 29624.7 | 1 | UniProt (P12319) Pfam (PF13927) Pfam (PF13895) | Homo sapiens (human) | Fc-epsilon RI-alpha,FcERI,IgE Fc receptor subunit alpha |
| 2 | B, C (D, E) | Isoform 1 of Immunoglobulin heavy constant epsilon | polymer | 353 | 39368.3 | 2 | UniProt (P01854) Pfam (PF07654) | Homo sapiens (human) | Ig epsilon chain C region,Ig epsilon chain C region ND |
| 3 | D (B) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 789.7 | 1 | In PDB GlyTouCan (G95663PY) | |||
| 4 | E (C) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 5 | F, G (F, G) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 2 | In PDB GlyTouCan (G15407YE) | |||
| 6 | H, I, J, K, L (A, E) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 5 | Chemie (NAG) |
Sequence modifications
D, E: 106 - 428 (UniProt: P01854)
| PDB | External Database | Details |
|---|---|---|
| Met 82 | - | initiating methionine |
| Ser 83 | - | expression tag |
| Val 84 | - | expression tag |
| Pro 85 | - | expression tag |
| Thr 86 | - | expression tag |
| Gln 87 | - | expression tag |
| Val 88 | - | expression tag |
| Leu 89 | - | expression tag |
| Gly 90 | - | expression tag |
| Leu 91 | - | expression tag |
| Leu 92 | - | expression tag |
| Leu 93 | - | expression tag |
| Leu 94 | - | expression tag |
| Trp 95 | - | expression tag |
| Leu 96 | - | expression tag |
| Thr 97 | - | expression tag |
| Asp 98 | - | expression tag |
| Ala 99 | - | expression tag |
| Arg 100 | - | expression tag |
| Cys 101 | - | expression tag |
| Asp 102 | - | expression tag |
| Ile 103 | - | expression tag |
| Val 104 | - | expression tag |
| Ala 105 | - | expression tag |
| His 429 | - | expression tag |
| His 430 | - | expression tag |
| His 431 | - | expression tag |
| His 432 | - | expression tag |
| His 433 | - | expression tag |
| His 434 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 108361.3 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 2387.2 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1106.0 | |
| All* | Total formula weight | 111854.6 |
