8Z0F
Cryo-EM structure of ATP-bound human very long-chain fatty acid ABC transporter ABCD3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | ATP-binding cassette sub-family D member 3 | polymer | 668 | 76678.2 | 2 | UniProt (P28288) Pfam (PF06472) Pfam (PF00005) | Homo sapiens (human) | 70 kDa peroxisomal membrane protein,PMP70 |
| 2 | C, D (A) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 2 | Chemie (ATP) |
Sequence modifications
A, B: 50 - 659 (UniProt: P28288)
| PDB | External Database | Details |
|---|---|---|
| Met -8 | - | initiating methionine |
| Asp -7 | - | expression tag |
| Tyr -6 | - | expression tag |
| Lys -5 | - | expression tag |
| Asp -4 | - | expression tag |
| Asp -3 | - | expression tag |
| Asp -2 | - | expression tag |
| Asp -1 | - | expression tag |
| Lys 0 | - | expression tag |
| Ala 1 | - | expression tag |
| Val 2 | - | expression tag |
| Phe 3 | - | expression tag |
| Ser 4 | - | expression tag |
| Lys 5 | - | expression tag |
| Leu 6 | - | expression tag |
| Gln 7 | - | expression tag |
| Leu 8 | - | expression tag |
| Leu 9 | - | expression tag |
| Gly 10 | - | expression tag |
| Gln 11 | - | expression tag |
| Ala 12 | - | expression tag |
| Ile 13 | - | expression tag |
| Pro 14 | - | expression tag |
| Pro 15 | - | expression tag |
| Lys 16 | - | expression tag |
| Gln 17 | - | expression tag |
| Tyr 18 | - | expression tag |
| Ala 19 | - | expression tag |
| Pro 20 | - | expression tag |
| Gly 21 | - | expression tag |
| Val 22 | - | expression tag |
| Val 23 | - | expression tag |
| Gly 24 | - | expression tag |
| Met 25 | - | expression tag |
| Leu 26 | - | expression tag |
| Ala 27 | - | expression tag |
| Val 28 | - | expression tag |
| Phe 29 | - | expression tag |
| Ala 30 | - | expression tag |
| Leu 31 | - | expression tag |
| Ile 32 | - | expression tag |
| Lys 33 | - | expression tag |
| Leu 34 | - | expression tag |
| Tyr 35 | - | expression tag |
| Lys 36 | - | expression tag |
| Gln 37 | - | expression tag |
| Asp 38 | - | expression tag |
| Ile 39 | - | expression tag |
| Arg 40 | - | expression tag |
| Gly 41 | - | expression tag |
| Thr 42 | - | expression tag |
| Lys 43 | - | expression tag |
| His 44 | - | expression tag |
| Leu 45 | - | expression tag |
| Val 46 | - | expression tag |
| Ala 47 | - | expression tag |
| Lys 48 | - | expression tag |
| Thr 49 | - | expression tag |
| Gln 596 | Glu 596 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 153356.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1014.4 | |
| All* | Total formula weight | 154370.7 |
