8YXY
NADPH and 1-benzyl-4-methylpiperidin-3-one complex structure of Imine Reductase Mutant(M6) from Pochonia chlamydosporia 170
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Oxidoreductase | polymer | 293 | 30554.1 | 2 | UniProt (A0A179FZ20) Pfam (PF03446) Pfam (PF21761) | Pochonia chlamydosporia 170 | Imine reductase |
| 2 | C, F (A, B) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 2 | Chemie (NAP) | |||
| 3 | D, G (A, B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
| 4 | E, H (A, B) | (4~{R})-4-methyl-1-(phenylmethyl)piperidin-3-one | non-polymer | 203.3 | 2 | Chemie (A1D7O) | |||
| 5 | I, J (A, B) | water | water | 18.0 | 704 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 293 (UniProt: A0A179FZ20)
| PDB | External Database | Details |
|---|---|---|
| Glu 40 | Ser 40 | conflict |
| Pro 47 | Ala 47 | conflict |
| Ala 50 | Val 50 | conflict |
| Asn 72 | Ser 72 | conflict |
| Gln 73 | Tyr 73 | conflict |
| Val 76 | Thr 76 | conflict |
| Thr 124 | Val 124 | conflict |
| Thr 125 | Pro 125 | conflict |
| Glu 127 | Ile 127 | conflict |
| Tyr 128 | Leu 128 | conflict |
| Val 178 | Ile 178 | conflict |
| Ser 180 | Gly 180 | conflict |
| Ala 195 | Lys 195 | conflict |
| Leu 210 | Phe 210 | conflict |
| Ala 212 | Lys 212 | conflict |
| Gln 217 | Trp 217 | conflict |
| Val 220 | Arg 220 | conflict |
| Arg 224 | His 224 | conflict |
| Ile 236 | Leu 236 | conflict |
| Gly 239 | Gln 239 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 61108.1 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 2105.6 | |
| All* | Total formula weight | 63213.7 |
