8YX3
Crystal Structure of SARS CoV-2 Papain-like Protease PLpro-C111S in Complex with GZNL-P28
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Papain-like protease nsp3 | polymer | 316 | 35712.5 | 2 | UniProt (P0DTD1) Pfam (PF08715) | Severe acute respiratory syndrome coronavirus 2 | Non-structural protein 3,nsp3,PL2-PRO,Papain-like proteinase,PL-PRO |
| 2 | C, D (A, B) | ~{N}-[1-(1,2-dihydroacenaphthylen-5-yl)cyclopropyl]-5-[(3~{S})-4-ethyl-3-methyl-piperazin-1-yl]-2-methyl-benzamide | non-polymer | 453.6 | 2 | Chemie (A1LZ7) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 59 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 315 (UniProt: P0DTD1)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
| Ser 111 | Cys 1674 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 71425.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 907.2 | |
| All* | Total formula weight | 72332.2 |
