8YWR
Crystal structure of the Fab fragment of the anti-IL-6 antibody 68F2 in complex with a domain-swapped IL-6 dimer
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Interleukin-6 | polymer | 171 | 19670.5 | 1 | UniProt (P05231) Pfam (PF00489) | Homo sapiens (human) | IL-6,B-cell stimulatory factor 2,BSF-2,CTL differentiation factor,CDF,Hybridoma growth factor,Interferon beta-2,IFN-beta-2 |
| 2 | B (H) | Heavy chain of the Fab fragment of anti-IL-6 antibody 68F2 | polymer | 222 | 23822.4 | 1 | Lama glama | ||
| 3 | C (L) | Light chain of the Fab fragment of anti-IL-6 antibody 68F2 | polymer | 216 | 22949.5 | 1 | Lama glama | ||
| 4 | D, E (L) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 5 | F, G (H, L) | water | water | 18.0 | 5 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 66442.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 192.1 | |
| All* | Total formula weight | 66634.5 |
