8YVL

Neuraminidase of A/California/04/2009 HIN1 in complex with CAV-F34 Fab

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Vasodilator-stimulated phosphoprotein,Neuraminidase	polymer	466	51660.8	4	UniProt (P50552) UniProt (A0A2R4G842) Pfam (PF08776)	Homo sapiens (human)	VASP
2	E, F, G, H (E, F, G, H)	CAV-F34 kappa chain	polymer	107	11500.8	4		Homo sapiens
3	I, J, K, L (I, J, K, L)	CAV-F34 heavy chain	polymer	123	13463.9	4		Homo sapiens
4	CA, DA, EA, M, N... (D, A, B, C)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	12	Chemie (NAG)
5	AA, BA, FA, GA, P... (C, D, A, B)	CALCIUM ION	non-polymer		40.1	9	Chemie (CA)

Sequence modifications

A, B, C, D: 32 - 74 (UniProt: P50552)

PDB	External Database	Details
Met 4	-	initiating methionine
Glu 5	-	expression tag
Phe 6	-	expression tag
Gly 7	-	expression tag
Leu 8	-	expression tag
Ser 9	-	expression tag
Trp 10	-	expression tag
Ile 11	-	expression tag
Phe 12	-	expression tag
Leu 13	-	expression tag
Ala 14	-	expression tag
Ala 15	-	expression tag
Ile 16	-	expression tag
Leu 17	-	expression tag
Lys 18	-	expression tag
Gly 19	-	expression tag
Val 20	-	expression tag
Gln 21	-	expression tag
Cys 22	-	expression tag
Ala 23	-	expression tag
Asp 24	-	expression tag
Pro 25	-	expression tag
His 26	-	expression tag
His 27	-	expression tag
His 28	-	expression tag
His 29	-	expression tag
His 30	-	expression tag
His 31	-	expression tag
Leu 75	-	linker
Val 76	-	linker
Pro 77	-	linker
Arg 78	-	linker
Gly 79	-	linker
Ser 80	-	linker
Gly 81	-	linker
Gly 82	-	linker

A, B, C, D: 83 - 469 (UniProt: A0A2R4G842)

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	306502.2
Non-Polymers*	Number of molecules	21
	Total formula weight	3015.2
All*	Total formula weight	309517.4

*Water molecules are not included.