8YV8
Cryo-EM structure of CDCA7 bound to nucleosome including hemimethylated CpG site in Widom601 positioning sequence.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E (A, E) | Histone H3.1 | polymer | 135 | 15306.0 | 2 | UniProt (P68431) Pfam (PF00125) | Homo sapiens (human) | Histone H3/a,Histone H3/b,Histone H3/c,Histone H3/d,Histone H3/f,Histone H3/h,Histone H3/i,Histone H3/j,Histone H3/k,Histone H3/l |
| 2 | B, F (B, F) | Histone H4 | polymer | 102 | 11263.2 | 2 | UniProt (P62805) Pfam (PF15511) | Homo sapiens (human) | |
| 3 | C, G (C, G) | Histone H2A type 1-B/E | polymer | 129 | 14034.4 | 2 | UniProt (P04908) Pfam (PF00125) Pfam (PF16211) | Homo sapiens (human) | Histone H2A.2,Histone H2A/a,Histone H2A/m |
| 4 | D, H (D, H) | Histone H2B type 1-K | polymer | 125 | 13790.0 | 2 | UniProt (O60814) Pfam (PF00125) | Homo sapiens (human) | H2B K,HIRA-interacting protein 1 |
| 5 | I (I) | DNA (132-MER) | polymer | 145 | 44534.4 | 1 | synthetic construct | ||
| 6 | J (J) | DNA (132-MER) | polymer | 145 | 44991.7 | 1 | synthetic construct | ||
| 7 | K (K) | Cell division cycle-associated protein 7 | polymer | 108 | 12350.1 | 1 | UniProt (Q9BWT1) Pfam (PF10497) | Homo sapiens (human) | Protein JPO1 |
| 8 | L, M, N (K) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) |
Sequence modifications
K: 264 - 371 (UniProt: Q9BWT1)
| PDB | External Database | Details |
|---|---|---|
| Ser 339 | Cys 339 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 11 |
| Total formula weight | 210663.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 196.2 | |
| All* | Total formula weight | 210859.6 |
