8YU9

Tubulin-RB3-TTL in complex with compound SI10

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	Detyrosinated tubulin alpha-1B chain	polymer	440	48966.3	2	UniProt (Q2XVP4) Pfam (PF00091) Pfam (PF03953)	Sus scrofa (pig)
2	B, D (B, D)	Tubulin beta chain	polymer	431	48391.4	2	UniProt (A0A8D0VN39) Pfam (PF00091) Pfam (PF03953) UniProt (by SIFTS) (A0A287AGU7)	Sus scrofa (pig)
3	E (E)	Stathmin-4	polymer	143	16844.2	1	UniProt (P63043) Pfam (PF00836)	Rattus norvegicus (Norway rat)	Stathmin-like protein B3,RB3
4	F (F)	Tubulin--tyrosine ligase	polymer	380	43825.9	1	UniProt (A0A8C9FGJ1) Pfam (PF03133) UniProt (by SIFTS) (A0A8V0Z8P0)	Gallus gallus (chicken)
5	G, O (A, C)	GUANOSINE-5'-TRIPHOSPHATE	non-polymer		523.2	2	Chemie (GTP)
6	H, P (A, C)	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)
7	I, N, Q (A, B, C)	MAGNESIUM ION	non-polymer		24.3	3	Chemie (MG)
8	J, R (B, D)	4-(2-chloranylthieno[3,2-d]pyrimidin-4-yl)-7-methoxy-1,3-dihydroquinoxalin-2-one	non-polymer		346.8	2	Chemie (A1D7A)
9	K, S (B, D)	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	2	Chemie (GDP)
10	L, M (B)	2-(N-MORPHOLINO)-ETHANESULFONIC ACID	non-polymer		195.2	2	Chemie (MES)
11	T (F)	PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER	non-polymer		505.2	1	Chemie (ACP)

Sequence modifications

E: 5 - 145 (UniProt: P63043)

PDB	External Database	Details
Met 3	-	initiating methionine
Ala 4	-	expression tag

F: 1 - 378 (UniProt: A0A8C9FGJ1)

PDB	External Database	Details
His 379	-	expression tag
His 380	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	255385.5
Non-Polymers*	Number of molecules	14
	Total formula weight	3675.1
All*	Total formula weight	259060.6

*Water molecules are not included.