8YTE
Crystal Structure of TrkA D5 domain in complex with macrocyclic peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | High affinity nerve growth factor receptor | polymer | 102 | 11221.6 | 2 | UniProt (P04629) | Homo sapiens (human) | Neurotrophic tyrosine kinase receptor type 1,TRK1-transforming tyrosine kinase protein,Tropomyosin-related kinase A,Tyrosine kinase receptor,Tyrosine kinase receptor A,Trk-A,gp140trk,p140-TrkA |
| 2 | B, D (B, D) | Macrocyclic Peptide | polymer | 14 | 1620.9 | 2 | synthetic construct | ||
| 3 | E, F, G, I, J... (A, B, C, D) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 9 | Chemie (EDO) | |||
| 4 | H, N (B, D) | AMINOMETHYLAMIDE | non-polymer | 74.1 | 2 | Chemie (GM1) | |||
| 5 | P, Q, R, S (A, B, C, D) | water | water | 18.0 | 91 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 25684.9 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 706.8 | |
| All* | Total formula weight | 26391.7 |
