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8YR2

Structure of NET-Nisoxetine in outward-open state

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(B, A)
Sodium-dependent noradrenaline transporterpolymer61769386.52UniProt (P23975)
Pfam (PF00209)
Homo sapiens (human)Norepinephrine transporter,NET,Solute carrier family 6 member 2
2C, U
(B, A)
nisoxetinenon-polymer271.42Chemie (41U)
3D, V
(B, A)
[(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoatenon-polymer746.62Chemie (PIO)
4E, F, W, X
(B, A)
SODIUM IONnon-polymer23.04Chemie (NA)
5G, Y
(B, A)
CHLORIDE IONnon-polymer35.52Chemie (CL)
6AA, BA, CA, DA, GA...
(A, B)
CHOLESTEROLnon-polymer386.720Chemie (CLR)
7EA, FA, O, P
(A, B)
[(2R)-2-octanoyloxy-3-[oxidanyl-[(2R,3R,5S,6R)-2,3,4,5,6-pentakis(oxidanyl)cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoatenon-polymer586.64Chemie (A1LX7)
8KA, LA
(B, A)
waterwater18.06Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight138773.1
Non-Polymers*Number of molecules34
Total formula weight12278.2
All*Total formula weight151051.3
*Water molecules are not included.

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PDB entries from 2024-10-30

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