8YPZ
Crystal strcture of human phosphoribosyl pyrophosphate synthetase 1 (PRPS1) in complex with GDP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Ribose-phosphate pyrophosphokinase 1 | polymer | 318 | 34835.1 | 6 | UniProt (P60891) Pfam (PF13793) Pfam (PF14572) | Homo sapiens (human) | PPRibP,Phosphoribosyl pyrophosphate synthase I,PRS-I |
| 2 | G, K, M, P, U... (A, B, C, D, E) | DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER | non-polymer | 505.2 | 6 | Chemie (APC) | |||
| 3 | BA, H, N, Q, Y (F, A, B, C, E) | 5-O-phosphono-alpha-D-ribofuranose | non-polymer | 230.1 | 5 | Chemie (HSX) | |||
| 4 | AA, I, J, R, S... (F, A, C, E) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 6 | Chemie (GDP) | |||
| 5 | CA, L, O, T, V... (F, A, B, C, D) | PHOSPHATE ION | non-polymer | 95.0 | 6 | Chemie (PO4) | |||
| 6 | DA, EA, FA, GA, HA... (A, B, C, D, E...) | water | water | 18.0 | 63 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 2 - 318 (UniProt: P60891)
| PDB | External Database | Details |
|---|---|---|
| Ser 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 209010.7 | |
| Non-Polymers* | Number of molecules | 23 |
| Total formula weight | 7410.8 | |
| All* | Total formula weight | 216421.6 |
