8YNZ

The structure of EfpA_BRD-8000.3 complex

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Uncharacterized MFS-type transporter EfpA	polymer	569	59671.4	2	UniProt (P9WJY5) Pfam (PF07690)	Mycobacterium tuberculosis H37Rv	Efflux protein A
2	C, D (A, B)	(1S,3S)-N-[6-bromo-5-(pyrimidin-2-yl)pyridin-2-yl]-2,2-dimethyl-3-(2-methylprop-1-en-1-yl)cyclopropane-1-carboxamide	non-polymer		401.3	2	Chemie (A1AQR)

Sequence modifications

A, B: 1 - 530 (UniProt: P9WJY5)

PDB	External Database	Details
Ala 531	-	expression tag
Ala 532	-	expression tag
Ala 533	-	expression tag
Glu 534	-	expression tag
Asn 535	-	expression tag
Leu 536	-	expression tag
Tyr 537	-	expression tag
Phe 538	-	expression tag
Gln 539	-	expression tag
Gly 540	-	expression tag
Leu 541	-	expression tag
Trp 542	-	expression tag
Ser 543	-	expression tag
His 544	-	expression tag
Pro 545	-	expression tag
Gln 546	-	expression tag
Phe 547	-	expression tag
Glu 548	-	expression tag
Lys 549	-	expression tag
Gly 550	-	expression tag
Gly 551	-	expression tag
Gly 552	-	expression tag
Ser 553	-	expression tag
Gly 554	-	expression tag
Gly 555	-	expression tag
Gly 556	-	expression tag
Ser 557	-	expression tag
Gly 558	-	expression tag
Gly 559	-	expression tag
Ser 560	-	expression tag
Ala 561	-	expression tag
Trp 562	-	expression tag
Ser 563	-	expression tag
His 564	-	expression tag
Pro 565	-	expression tag
Gln 566	-	expression tag
Phe 567	-	expression tag
Glu 568	-	expression tag
Lys 569	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	119342.9
Non-Polymers*	Number of molecules	2
	Total formula weight	802.6
All*	Total formula weight	120145.5

*Water molecules are not included.