8YLP

Overall structure of the y+LAT1-4F2hc bound with Arg

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Amino acid transporter heavy chain SLC3A2	polymer	645	69837.5	1	UniProt (P08195) Pfam (PF16028) Pfam (PF00128)	Homo sapiens (human)	4F2 cell-surface antigen heavy chain,4F2hc,4F2 heavy chain antigen,Lymphocyte activation antigen 4F2 large subunit,Solute carrier family 3 member 2
2	B (B)	Y+L amino acid transporter 1	polymer	529	57963.1	1	UniProt (Q9UM01) Pfam (PF13520)	Homo sapiens (human)	Monocyte amino acid permease 2,MOP-2,Solute carrier family 7 member 7,y(+)L-type amino acid transporter 1,Y+LAT1,y+LAT-1
3	C, D, E, F (C, D, E, F)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	4	In PDB GlyTouCan (G42666HT)
4	G (B)	ARGININE	non-polymer		175.2	1	Chemie (ARG)

Sequence modifications

A: 3 - 631 (UniProt: P08195)

PDB	External Database	Details
His -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
Ser 0	-	expression tag
Gly 1	-	expression tag
Arg 2	-	expression tag
Thr 632	-	expression tag
Gly 633	-	expression tag
Ala 634	-	expression tag

B: 2 - 511 (UniProt: Q9UM01)

PDB	External Database	Details
Asp -17	-	expression tag
Tyr -16	-	expression tag
Lys -15	-	expression tag
Asp -14	-	expression tag
Asp -13	-	expression tag
Asp -12	-	expression tag
Asp -11	-	expression tag
Lys -10	-	expression tag
Ser -9	-	expression tag
Gly -8	-	expression tag
Pro -7	-	expression tag
Asp -6	-	expression tag
Glu -5	-	expression tag
Val -4	-	expression tag
Asp -3	-	expression tag
Ala -2	-	expression tag
Ser -1	-	expression tag
Gly 0	-	expression tag
Arg 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	127800.7
Branched	Number of molecules	4
	Total formula weight	1697.6
Non-Polymers*	Number of molecules	1
	Total formula weight	175.2
All*	Total formula weight	129673.5

*Water molecules are not included.