8YKH
Structure of SARS-CoV-2 spike RBD in complex with NT-108 scFv
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | NT-108 scFv | polymer | 251 | 26820.6 | 1 | Homo sapiens | ||
| 2 | B (B) | Spike glycoprotein | polymer | 1199 | 132754.9 | 1 | UniProt (P0DTC2) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) | Severe acute respiratory syndrome coronavirus 2 | S glycoprotein,E2,Peplomer protein |
| 3 | C (C) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) |
Sequence modifications
B: 12 - 1210 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Gly 682 | Arg 682 | engineered mutation |
| Ser 683 | Arg 683 | engineered mutation |
| Gly 685 | Arg 685 | engineered mutation |
| Pro 817 | Phe 817 | engineered mutation |
| Pro 892 | Ala 892 | engineered mutation |
| Pro 899 | Ala 899 | engineered mutation |
| Pro 942 | Ala 942 | engineered mutation |
| Pro 986 | Lys 986 | engineered mutation |
| Pro 987 | Val 987 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 159575.6 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 424.4 | |
| All* | Total formula weight | 160000.0 |
