8YJZ
Structure of the human endogenous PCNA-FEN1-RNase H2 complex - State D
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, F, G (B, C, A) | Proliferating cell nuclear antigen | polymer | 261 | 28795.8 | 3 | UniProt (P12004) Pfam (PF00705) Pfam (PF02747) | Homo sapiens | PCNA,Cyclin |
| 2 | B (D) | Flap endonuclease 1 | polymer | 380 | 42661.1 | 1 | UniProt (P39748) Pfam (PF00752) Pfam (PF00867) | Homo sapiens | FEN-1,DNase IV,Flap structure-specific endonuclease 1,Maturation factor 1,MF1,hFEN-1 |
| 3 | C (H) | Ribonuclease H2 subunit A | polymer | 299 | 33431.8 | 1 | UniProt (O75792) Pfam (PF01351) | Homo sapiens | RNase H2 subunit A,Aicardi-Goutieres syndrome 4 protein,AGS4,RNase H(35),Ribonuclease HI large subunit,RNase HI large subunit,Ribonuclease HI subunit A |
| 4 | D (G) | Ribonuclease H2 subunit B | polymer | 312 | 35195.7 | 1 | UniProt (Q5TBB1) Pfam (PF17745) Pfam (PF09468) | Homo sapiens | RNase H2 subunit B,Aicardi-Goutieres syndrome 2 protein,AGS2,Deleted in lymphocytic leukemia 8,Ribonuclease HI subunit B |
| 5 | E (I) | Ribonuclease H2 subunit C | polymer | 164 | 17862.1 | 1 | UniProt (Q8TDP1) Pfam (PF08615) | Homo sapiens | RNase H2 subunit C,Aicardi-Goutieres syndrome 3 protein,AGS3,RNase H1 small subunit,Ribonuclease HI subunit C |
| 6 | H (J) | upstream DNA | polymer | 20 | 6102.0 | 1 | Homo sapiens | ||
| 7 | I (E) | parent strand DNA | polymer | 31 | 9565.3 | 1 | Homo sapiens | ||
| 8 | J (F) | downstream DNA | polymer | 14 | 4249.8 | 1 | Homo sapiens |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 235455.1 | |
| All* | Total formula weight | 235455.1 |
