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8YIV

N17.1.2 recognition of NRAS neoantigens

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
MHC class I antigenpolymer27631897.31UniProt (F6IQR9)
Pfam (PF00129)
Pfam (PF07654)
Homo sapiens (human)
2B
(C)
ILE-LEU-ASP-THR-ALA-GLY-LYS-GLU-GLU-TYRpolymer101139.21UniProt (by SIFTS) (P01116)Homo sapiens
3C
(B)
Beta-2-microglobulinpolymer10011879.41UniProt (P61769)
Pfam (PF07654)
Homo sapiens (human)
4D
(D)
TCR ALPHApolymer20723074.81Pfam (PF09291)
UniProt (by SIFTS) (P01848)
Homo sapiens
5E
(E)
TCR betapolymer24728186.71Pfam (PF07686)
Pfam (PF07654)
UniProt (by SIFTS) (P0DTU4)
Homo sapiens
6F, G, H, J, L...
(A, D, E)
GLYCEROLnon-polymer92.18Chemie (GOL)
7I, K
(A, E)
1,2-ETHANEDIOLnon-polymer62.12Chemie (EDO)
8P, Q, R, S, T
(A, C, B, D, E)
waterwater18.0547Chemie (HOH)
Sequence modifications
A: 1 - 275 (UniProt: F6IQR9)
PDBExternal DatabaseDetails
Met 0-initiating methionine
B: 1 - 99 (UniProt: P61769)
PDBExternal DatabaseDetails
Met 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight96177.3
Non-Polymers*Number of molecules10
Total formula weight860.9
All*Total formula weight97038.2
*Water molecules are not included.

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PDB entries from 2025-07-02

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