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8YHW

The Crystal Structure of NF-kB-inducing Kinase (NIK) from Biortus

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Mitogen-activated protein kinase kinase kinase 14polymer35138728.24UniProt (Q99558)
Pfam (PF00069)
Homo sapiens (human)NF-kappa-beta-inducing kinase,HsNIK,Serine/threonine-protein kinase NIK
2E, H, K, N
(A, B, C, D)
PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTERnon-polymer523.24Chemie (AGS)
3F, I, L, O
(A, B, C, D)
MAGNESIUM IONnon-polymer24.34Chemie (MG)
4G, J, M, Q, R
(A, B, C, D)
1,2-ETHANEDIOLnon-polymer62.15Chemie (EDO)
5P
(D)
3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOLnon-polymer370.41Chemie (PE8)
6S, T, U, V
(A, B, C, D)
waterwater18.0147Chemie (HOH)
Sequence modifications
A, B, C, D: 330 - 679 (UniProt: Q99558)
PDBExternal DatabaseDetails
Gly 329-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight154912.9
Non-Polymers*Number of molecules14
Total formula weight2871.0
All*Total formula weight157783.9
*Water molecules are not included.

250059

PDB entries from 2026-03-04

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