8YFT

Cryo-EM structure of SARS-CoV-2 alpha variant spike protein in complex with raccoon dog ACE2 (local refinement)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Angiotensin-converting enzyme	polymer	605	70600.1	1	UniProt (B4XEP4) Pfam (PF01401)	Nyctereutes procyonoides (raccoon dog)
2	B (B)	Spike protein S1	polymer	223	25171.4	1	UniProt (P0DTC2) Pfam (PF09408)	Severe acute respiratory syndrome coronavirus 2
3	C, D, E, F (C, D, E, F)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	4	In PDB GlyTouCan (G42666HT)
4	G (A)	ZINC ION	non-polymer		65.4	1	Chemie (ZN)
5	H (A)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)

Sequence modifications

A: 19 - 617 (UniProt: B4XEP4)

PDB	External Database	Details
His 618	-	expression tag
His 619	-	expression tag
His 620	-	expression tag
His 621	-	expression tag
His 622	-	expression tag
His 623	-	expression tag

B: 319 - 541 (UniProt: P0DTC2)

PDB	External Database	Details
Tyr 501	Asn 501	variant

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	95771.5
Branched	Number of molecules	4
	Total formula weight	1697.6
Non-Polymers*	Number of molecules	2
	Total formula weight	286.6
All*	Total formula weight	97755.7

*Water molecules are not included.