8YEV

Dual-specificity tyrosine phosphorylation-regulated kinase 1A in complex with coumestrol

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	polymer	360	42025.5	2	UniProt (Q13627) Pfam (PF00069)	Homo sapiens	Dual specificity YAK1-related kinase,HP86,Protein kinase minibrain homolog,MNBH,hMNB
2	C, D (A, B)	Coumestrol	non-polymer		268.2	2	Chemie (CUE)
3	E, F (A, B)	water	water		18.0	434	Chemie (HOH)

Sequence modifications

A, B: 134 - 481 (UniProt: Q13627)

PDB	External Database	Details
Met 133	-	initiating methionine
Gly 482	-	expression tag
Ala 483	-	expression tag
Ala 484	-	expression tag
His 485	-	expression tag
His 486	-	expression tag
His 487	-	expression tag
His 488	-	expression tag
His 489	-	expression tag
His 490	-	expression tag
His 491	-	expression tag
His 492	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	84051.0
Non-Polymers*	Number of molecules	2
	Total formula weight	536.4
All*	Total formula weight	84587.4

*Water molecules are not included.