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8YE9

Cryo-EM structure of Cas9-sgRNA-A25 complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
CRISPR-associated endonuclease Cas9/Csn1polymer1368158699.81UniProt (Q99ZW2)
Pfam (PF16593)
Pfam (PF16592)
Pfam (PF13395)
Pfam (PF22702)
Pfam (PF16595)
Streptococcus pyogenes serotype M1SpCas9,SpyCas9
2B
(C)
RNA (98-MER)polymer9831718.91Streptococcus pyogenes
3C
(B)
A25polymer10111899.61UniProt (K8MKB3)Streptococcus sp. F0441
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight202318.4
All*Total formula weight202318.4
*Water molecules are not included.

247947

PDB entries from 2026-01-21

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