8Y9V

ZIKV NS2B/NS3 protease

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	Serine protease subunit NS2B	polymer	53	5865.4	2	UniProt (H8XX12) Pfam (PF01002) UniProt (by SIFTS) (Q32ZE1)	Zika virus
2	B (B)	Serine protease NS3	polymer	153	16354.6	1	UniProt (Q32ZE1) Pfam (PF00949)	Zika virus	Flavivirin protease NS3 catalytic subunit,Non-structural protein 3
3	D (D)	Serine protease NS3	polymer	161	17285.6	1	UniProt (Q32ZE1) Pfam (PF00949)	Zika virus	Flavivirin protease NS3 catalytic subunit,Non-structural protein 3
4	E (E)	DAR-LYS-ORN-ARG	polymer	4	575.7	1		synthetic construct
5	F, G, H, I (A, B, C, D)	water	water		18.0	163	Chemie (HOH)

Sequence modifications

A, C: 2 - 53 (UniProt: H8XX12)

PDB	External Database	Details
Met 1	-	initiating methionine

B: 18 - 170 (UniProt: Q32ZE1)

PDB	External Database	Details
Lys 107	Arg 1605	conflict
Ser 143	Cys 1641	conflict

D: 13 - 173 (UniProt: Q32ZE1)

PDB	External Database	Details
Lys 107	Arg 1605	conflict
Ser 143	Cys 1641	conflict

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	45946.7
All*	Total formula weight	45946.7

*Water molecules are not included.