8Y8F
Structure of HCoV-HKU1C spike in the glycan-activated-closed conformation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Spike glycoprotein | polymer | 1263 | 140242.5 | 3 | UniProt (Q0ZME7) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) | Human coronavirus HKU1 (isolate N5) (HCoV-HKU1) | S glycoprotein,E2,Peplomer protein |
| 2 | D, E, G (D, E, G) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 3 | In PDB GlyTouCan (G42666HT) | |||
| 3 | F (F) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 4 | AA, BA, CA, DA, EA... (B, C, A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 32 | Chemie (NAG) |
Sequence modifications
A, B, C: 14 - 1276 (UniProt: Q0ZME7)
| PDB | External Database | Details |
|---|---|---|
| Gly 752 | Arg 752 | engineered mutation |
| Gly 753 | Arg 753 | engineered mutation |
| Ser 754 | Lys 754 | engineered mutation |
| Gly 755 | Arg 755 | engineered mutation |
| Ser 756 | Arg 756 | engineered mutation |
| Pro 902 | Leu 902 | engineered mutation |
| Pro 980 | Ser 980 | engineered mutation |
| Pro 1023 | Asn 1023 | engineered mutation |
| Pro 1067 | Asn 1067 | engineered mutation |
| Pro 1068 | Leu 1068 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 420727.4 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 1859.7 | |
| Non-Polymers* | Number of molecules | 32 |
| Total formula weight | 7078.7 | |
| All* | Total formula weight | 429665.8 |
