8Y8D

Structure of HCoV-HKU1C spike in the inactive-1up conformation

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	C, A, B	Spike glycoprotein	polymer	1263	140242.5	3	UniProt (Q0ZME7) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) In PDB	Human coronavirus HKU1 (isolate N5) (HCoV-HKU1)	S glycoprotein,E2,Peplomer protein
2	D	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	1	In PDB GlyTouCan (G15407YE)
3	E	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
4	B, C, A	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	26	Chemie (NAG)

Sequence modifications

C, A, B: 14 - 1276 (UniProt: Q0ZME7)

PDB	External Database	Details
Gly 752	Arg 752	engineered mutation
Gly 753	Arg 753	engineered mutation
Ser 754	Lys 754	engineered mutation
Gly 755	Arg 755	engineered mutation
Ser 756	Arg 756	engineered mutation
Pro 902	Leu 902	engineered mutation
Pro 980	Ser 980	engineered mutation
Pro 1023	Asn 1023	engineered mutation
Pro 1067	Asn 1067	engineered mutation
Pro 1068	Leu 1068	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	420727.4
Branched	Number of molecules	2
	Total formula weight	1010.9
Non-Polymers*	Number of molecules	26
	Total formula weight	5751.4
All*	Total formula weight	427489.7

*Water molecules are not included.